Protein Info for Echvi_3868 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-galactosidase/beta-glucuronidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 878 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00703: Glyco_hydro_2" amino acids 247 to 340 (94 residues), 45.7 bits, see alignment E=1.6e-15 PF02836: Glyco_hydro_2_C" amino acids 351 to 514 (164 residues), 38.9 bits, see alignment E=8.6e-14 PF18368: Ig_GlcNase" amino acids 766 to 870 (105 residues), 97.8 bits, see alignment E=6.1e-32

Best Hits

KEGG orthology group: None (inferred from 66% identity to zpr:ZPR_4166)

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G5G9 at UniProt or InterPro

Protein Sequence (878 amino acids)

>Echvi_3868 Beta-galactosidase/beta-glucuronidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKTIRLYLPILLLLLFISSLCHAQDRYELNTDWYCQPIDDTQADGHALSNPSYPLTGWMP
ATVPGTVLTTLLNNGKVPDPFYGMNNEKIKDIYDTGREYYTYWFVKEFEESATDGEQVWL
NFRGINYSADIFLNGQKVNQTPFKGMYLRKQYNITKLLAKNGKNRLAVLVHPADHVGNPN
GGQGGDGTIAKGVALQYTAGWDWIQPVRDRNTGIWDKVFIEKTGTVNLKHPHIVTLVPGT
RIPGASQEPATLKVSAELQNVLDHSISGTLQYTLAGKTISQKVTLKPQETAEVALPDFTL
QNPKLWWPNGYGEQHLYAIDLQFTADGAVSDREKITFGVREIQTTWNSHTRSKEIAVNGQ
KIFIKGGNWIISDAMLRFSKARYDAEIRFHRDMNLNLIRIWGGALPERPEFYEACDRYGM
LVIQDFWMSGDCNGRWLDPKKKDDQWTRRQYPDDHGLFIESAADVVKMLRNHPSLAMWCG
GNEITPPADILKALKEDVLPKLDGTRWFIDYSNSDEMSYNFKGGNGDGPYGIQDISTFWA
EKTWPFNSEVGSVGTGDATSLKRFLPEENQVIPVEMDGTEKVRDEVWSYHKYIDYGNALE
PYGSPEDMEDFAAKAQLVNYNQYRGLIEGFTAHMWDWYTGVIIWKTQNPWTSLRGQMYDY
YLDPNASLYGLRNGSEVLHGMYDPVKGNIMIANNTFDQQHDIMLRVTAYDMQGNDQQLTQ
VFCYLEPTSIRLIMSLQERIKALSADEGMFLSVQLLNTDQKILSDNFYWLPDANGNYSGL
QRMEKANIQATATQSAPGEVSLKLTNPSGNTVSFFNRISLVDTESGERLLPTFFSDNYVS
LTPGEEKVVTVSYADLDKNSAAIEIGGWNTPLQTITIE