Protein Info for Echvi_3839 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 PF01323: DSBA" amino acids 4 to 205 (202 residues), 150.3 bits, see alignment E=5.8e-48

Best Hits

KEGG orthology group: None (inferred from 59% identity to dfe:Dfer_2694)

Predicted SEED Role

"2-hydroxychromene-2-carboxylate isomerase/DsbA-like thioredoxin domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4Y0 at UniProt or InterPro

Protein Sequence (237 amino acids)

>Echvi_3839 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis (Echinicola vietnamensis KMM 6221, DSM 17526)
MMKIEIWSDIMCPFCYIGKRRLEAALAEFPHKDDVEVVWKSFLLNPDMKTDLDKSIAQYL
AETKGWTVEQAEEAGNQVTEMAKEDGLEYHFDKVVVANGRVAHRLLQYAKTEGKGDAMKE
RLFKAYFTEGAHTADPDTLVKLAVEVGLDASKARESLDSKEFDLLVTQDIYESHQLGVRG
VPFFVLNEKYGVSGAQPKETFAQALETSWKDYAQEKPTVQDLSGDGDGAACDVDGNC