Protein Info for Echvi_3827 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Putative regulator of cell autolysis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 43 to 61 (19 residues), see Phobius details amino acids 75 to 95 (21 residues), see Phobius details amino acids 125 to 147 (23 residues), see Phobius details PF06580: His_kinase" amino acids 167 to 244 (78 residues), 83.7 bits, see alignment E=4.4e-28

Best Hits

KEGG orthology group: None (inferred from 36% identity to pdi:BDI_3356)

Predicted SEED Role

"putative two-component system sensor protein, no kinase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1H8 at UniProt or InterPro

Protein Sequence (358 amino acids)

>Echvi_3827 Putative regulator of cell autolysis (Echinicola vietnamensis KMM 6221, DSM 17526)
MYEGLKLHKHVSILIHILAWLLIGAVLFLLGPLSWNTTLPVEFWYRQLTLVVVLVAFFYT
NKDFFVPKLLFNGKNWLFLLVILGLCFTLMYAVEYFERLIRLPELMHEAFHPDDDKPYKP
KKDYIDVFLLLVLFLAAGISTSIAAVQKWQADETLRRQLDQQRISSELSYLKAQINPHFF
FNTLNNIYSLTSIDVESARIALHKLSRMMRYVLYETEKDQTLLSKEIGFIKDFIELMKLR
ISEKVQIELDIEDHVEDRVVAPMLLLPFVENCFKHGVSSRYPGIISIRIHTENDLLTLET
SNKIVPKNMGSPESHQHGIGLSNTKRRLSLLYHKKHELLIDDQNAENEYRVTLKINLA