Protein Info for Echvi_3816 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Arylsulfatase A and related enzymes

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00884: Sulfatase" amino acids 36 to 405 (370 residues), 193.6 bits, see alignment E=5.3e-61

Best Hits

Swiss-Prot: 49% identical to GALSF_BACTN: N-acetylgalactosamine-6-O-sulfatase (BT_3333) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: None (inferred from 72% identity to fbc:FB2170_03325)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G416 at UniProt or InterPro

Protein Sequence (518 amino acids)

>Echvi_3816 Arylsulfatase A and related enzymes (Echinicola vietnamensis KMM 6221, DSM 17526)
MVHIEHYCFAGLLLLLIGCKSNTQSKQEEETVAAHPNIVVIYMDDLGYGDMSAYGATEIS
TPHMDRLANEGIRFTNGYASSATCTPSRYALLTGTYPWRNKNAKILPGTAPLLIDTAQMT
LPKMLQQQGYYTGIVGKWHLGLGSGNVNWNEKISPSPNEVGFDYSHILAATQDRVPTVYI
ENGHVVNLDPNDPIAVDYQHNFEGEPTGKDNPEMLTMDWHHGHNNSIVNGVPRIGFMKGG
ASAKWSDVDMADHFLEKARTFVKGHKDKPFFLYYALQQPHVPRTPNPRFVGATGMGPRGD
VIAEADWCIGAFLKTLEEEGILENTLIVFSSDNGPVLNDGYVDDAVEKLGDHTPSGPLRG
GKYSLFEAGTRVPFAVYWKGKIQPSVSNALVCQLDLMSSLADLVGSDQKGPDSEDLLATF
LGEAPQGRDELILEASGRTALRQGDWIMIPPYKGPAIAKAVNIELGNADVYQLYNLKEDI
GQQQNLAQSNPEKLQEMVANYEKIRGVDQGEIEQLELK