Protein Info for Echvi_3757 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02231, adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC: 2.7.1.156 2.7.7.62] (inferred from 57% identity to fps:FP1461)Predicted SEED Role
"Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)" in subsystem Cobalamin synthesis or Coenzyme B12 biosynthesis (EC 2.7.7.62)
MetaCyc Pathways
- adenosylcobinamide-GDP salvage from cobinamide I (5/5 steps found)
- superpathway of adenosylcobalamin salvage from cobinamide I (7/8 steps found)
- adenosylcobinamide-GDP biosynthesis from cobyrinate a,c-diamide (4/6 steps found)
- adenosylcobinamide-GDP salvage from cobinamide II (4/6 steps found)
- adenosylcobinamide-GDP salvage from assorted adenosylcobamides (1/2 steps found)
- superpathway of adenosylcobalamin salvage from cobinamide II (6/9 steps found)
- adenosylcobalamin biosynthesis II (aerobic) (15/33 steps found)
- adenosylcobalamin biosynthesis I (anaerobic) (15/36 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.7.1.156 or 2.7.7.62
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G183 at UniProt or InterPro
Protein Sequence (169 amino acids)
>Echvi_3757 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase (Echinicola vietnamensis KMM 6221, DSM 17526) MIHYITGGERSGKSRYAQQLAESLTRAPIYLATSRIWDQDFQQRVDRHQADRDERWTTME VEKHIGQVDVAQKVVVMDCVTLWLTNWYGDAKGDITSCLKDCKAELAQLFASAQQGTLIV ISNEIGMGLHAQTETGRKFTELQGWINQYIAQRADKAVFMVSGLPLNLK