Protein Info for Echvi_3752 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1052 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 22 to 93 (72 residues), 37.4 bits, see alignment 4.2e-13 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 22 to 1052 (1031 residues), 843.5 bits, see alignment E=3.1e-257 PF13715: CarbopepD_reg_2" amino acids 23 to 104 (82 residues), 68 bits, see alignment 9.2e-23 PF07715: Plug" amino acids 112 to 231 (120 residues), 72.3 bits, see alignment E=6.9e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 207 to 237 (31 residues), 58.2 bits, see alignment (E = 5.5e-20)

Best Hits

KEGG orthology group: None (inferred from 57% identity to cpi:Cpin_6368)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G176 at UniProt or InterPro

Protein Sequence (1052 amino acids)

>Echvi_3752 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKCLLLGFLLLIAGITYAQVTVTGTVSAASDGEAIPGVSIIIKGTTKGVTTDLEGNYTI
TADADNVLVYSFIGYKPQEMSIGNQSVINIQLEEDISNLEEFVVVGYGTMKKSDMSSAHV
TVTSEDIEKTVNTTIEQAIQGRAAGVYVTKNTGAPGGGLSVNIRGINSIGGTNEPLYVID
GVQIQPNTVSYGPTSGTNPLAGLNPSDIESMEILQGPSATAIYGSRGTNGVVLITTKRGK
EGQTNINYSYLYSLQDKPDNLAVMNLQQYAEMTNTIRDLTGGDPPAAFLDPSLLGEGTDW
QDALYKTAALNKHTLSLSGGNESTKYYLSGEYFNQDGVAIGSGFERYSMRLNLDNEVRDW
LNIGVNLALNETDEQLATGSSDVINYAIQMAPNIPVQNPDGSWGGADPLNGSSLQFTPPN
PIALANLLDRTYKRRQALGGLNVGIDIMEGLRFTTQLNGNINYANGHFWTPTYTLGSVTN
DVNELTSKAENSFYWNWSQTLTYNKTFADKHDLTLMFTHEAQESNWESIEGSRQNFTSND
LPVLGLGSSQGATNAGNKNQWAMESYLGRINYTYDDKYIVLAALRADGSANFGPENRWGY
FPSVSAAWRVSEEDFMAGMAVVDELKIRLETGLTGNQGSANAIYAPLSSPSVPTPWGGGF
LVTRYGNPELAWEETQTYNVGFNLNMFNNRVQVEGDFYMKRTDNLLLPNPLPWYMGTEGE
GSIGTPTVNIGSLENRGYAFTINTVNIDNRATSFRWSSNFNFSGFKTEVTKFYSESAFID
RTAWYMNDFTQRAVIGQSPWLFYGYQYEGIFQSVEDIEGSAIPADNNGERLPIGEDDIWV
GDIKYRDLNGDNIIDERDQTFIGNPWPKFTFGTTQTFEYKGFKLDILLLGALGADVFNYA
RFNNTNPNNINLGRNLLVESFDYAKVETDSEGNPYLTNPGTDIPRITVTDPNGNGTRISD
KFVEDGSYVRLKNINLSYEFDKNLLGWQNVVRGARLSFGVQNLATWTKYKGYDPEVGAYV
GNNVDAANQLIGVDYGRYPSTRMYNFSLGIDF