Protein Info for Echvi_3709 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ribonuclease Z

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 TIGR02651: ribonuclease Z" amino acids 5 to 301 (297 residues), 299 bits, see alignment E=1.6e-93 PF00753: Lactamase_B" amino acids 25 to 106 (82 residues), 38 bits, see alignment E=1.8e-13 PF12706: Lactamase_B_2" amino acids 34 to 151 (118 residues), 34.4 bits, see alignment E=1.8e-12

Best Hits

Swiss-Prot: 46% identical to RNZ_BACFN: Ribonuclease Z (rnz) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)

KEGG orthology group: K00784, ribonuclease Z [EC: 3.1.26.11] (inferred from 53% identity to mtt:Ftrac_1526)

Predicted SEED Role

"Ribonuclease Z (EC 3.1.26.11)" in subsystem tRNA processing (EC 3.1.26.11)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G4I2 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Echvi_3709 ribonuclease Z (Echinicola vietnamensis KMM 6221, DSM 17526)
MEFSVTILGSNSAVPAHDRNQTSQIVTLGSKLLMIDCGEATQIQLQRYKIRSFKIDHIFI
SHLHGDHYLGLMGVISTFHLNKRKTPLTIYGPRGLDEIITTQLKYGNTKLNYPLHFVRTD
PDQKQLLVDAKKFMVYSFPLKHRLPCTGFLVVEKPGLRHIIKEKLLEQPLSIPAINVLKH
GKDYMDKDGNVFTVEEFTRPPDPIRKYAFCSDTIFDEELVPYLKGVDLLYHESTFMEAEC
ERAAETYHCTASQAATIAQKADVKQLLLGHYSTRYVELEPLWEEAKRVFDRCQLSTEGET
YSL