Protein Info for Echvi_3675 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-lactamase class C and other penicillin binding proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details PF00144: Beta-lactamase" amino acids 47 to 280 (234 residues), 148 bits, see alignment E=2e-47

Best Hits

KEGG orthology group: None (inferred from 79% identity to fbc:FB2170_09476)

Predicted SEED Role

"D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)" in subsystem Peptidoglycan Biosynthesis (EC 3.4.16.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.16.4

Use Curated BLAST to search for 3.4.16.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G105 at UniProt or InterPro

Protein Sequence (343 amino acids)

>Echvi_3675 Beta-lactamase class C and other penicillin binding proteins (Echinicola vietnamensis KMM 6221, DSM 17526)
MIKNKKAKSIVRIVLLVGTVISLFFVPWILVKAWVLPLPDTVQEQVDEAIGHGFDGMIVY
VDQAGKQPQFYTGGWKDRENKIPADPTSLFKIASISKLYTAVAATKLVKEKHLSFGKMLT
DYLPELRGRIENAEEITLKMMIQHRSGIPNFTNNPAFWENEEENGKNALDFALDLPASFK
PGKGYEYSNTNYLLLRMILDKVLGYNHHEYIKEKILKPLELNNTFFSINDVNLDDVMSGY
YVGIEEDFKARDNGMLATAEDVAIFIRALNNGSVFEEGEQEIYPYEYNHGGLVVGYQSLA
EYHKDIDAVVVQFINTTDFEGYEWNLSEITINRIVSIIRKKIH