Protein Info for Echvi_3632 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Altronate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 PF08666: SAF" amino acids 12 to 82 (71 residues), 27.8 bits, see alignment E=4.7e-10 PF04295: GD_AH_second" amino acids 113 to 289 (177 residues), 122.7 bits, see alignment E=1.8e-39 PF20629: GD_AH_C" amino acids 305 to 546 (242 residues), 322.8 bits, see alignment E=1.9e-100

Best Hits

KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 62% identity to lby:Lbys_1619)

Predicted SEED Role

"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G2S4 at UniProt or InterPro

Protein Sequence (548 amino acids)

>Echvi_3632 Altronate dehydratase (Echinicola vietnamensis KMM 6221, DSM 17526)
MLHKILKIHPKDNVLVALTDLKAGEQIEFEGNEITLTHDVKAKHKFAEAAFATDEDIYMY
GIICGKAMNAIAKGEVLTTQNVAHKTSEFTGVRDFKPWNAPDVSKWADRTFMGYHREDGQ
VGTANYWLVIPLVFCENRNIEIMKNAFVEELGFAKPNKYKSFVKQMKDLYTQGKKEEIAT
LSVETAEQDGESRIFKNIDGIKFLTHQAGCGGIRQDSEMLCGLIAGYINNPNVAGATILS
LGCQNAQPSILREKLDKINPDLKKPVIILEQQQEGTENTLLTNAIQKTFLALTDADQLER
QPAPLSKLTVGLECGGSDGFSGISANPSVGHASDLVVALGGKTILSEFPELCGVEQELIN
RCTTDESADKFVTLMRAYAASAEAVGSGFDMNPSPGNIKDGLITDAMKSAGAAKKGGTSP
IVDVLDYAEYVTKPGLNLLCTPGNDVESTTAMAGSGANVILFTTGLGTPTGNPVTPVLKV
SSNHILAEKMDDIIDINTGGVISGDKTIDQMGEEILEHIIEVASGNKKAKAMTLNQDDFI
PWKRGVSL