Protein Info for Echvi_3545 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ABC-type Mn2+/Zn2+ transport systems, permease components

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 147 to 166 (20 residues), see Phobius details amino acids 178 to 200 (23 residues), see Phobius details amino acids 207 to 227 (21 residues), see Phobius details amino acids 234 to 253 (20 residues), see Phobius details amino acids 259 to 278 (20 residues), see Phobius details PF00950: ABC-3" amino acids 11 to 278 (268 residues), 166 bits, see alignment E=1.2e-52 PF01032: FecCD" amino acids 45 to 278 (234 residues), 43.5 bits, see alignment E=2.2e-15

Best Hits

Swiss-Prot: 46% identical to MNTD_BACSU: Manganese transport system membrane protein MntD (mntD) from Bacillus subtilis (strain 168)

KEGG orthology group: K11709, manganese/zinc/iron transport system permease protein (inferred from 57% identity to mtt:Ftrac_0695)

Predicted SEED Role

"Manganese ABC transporter, inner membrane permease protein SitD" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G421 at UniProt or InterPro

Protein Sequence (301 amino acids)

>Echvi_3545 ABC-type Mn2+/Zn2+ transport systems, permease components (Echinicola vietnamensis KMM 6221, DSM 17526)
MSFDPNAFLIITTGSMIAISCGLLGVFLMLRKMAMTGDAISHAVLPGIVIAFLVSGSRHG
LTMVIGAGLVGILATVFIEYLSNKVKLQSDASIGITFTSLFALGIIMITFLANEIDLDQD
CVLYGEIAYVPIDLWITGSGKIIGPRVTYLSLINMVLVIGFIILFFKELKISTFDKEFAA
TLGLSTVGVNYALMGMVSYTTVSSFEAVGAILVVALMVVPPATAYLWTKNLYRLIQLTVV
LGVVISFLGYYMAYFLNSSIAGAMASVAGFFFFTTVILQRRQIPRIKKKLAAVKVGSWST
E