Protein Info for Echvi_3497 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: transporter, SSS family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 signal peptide" amino acids 5 to 5 (1 residues), see Phobius details transmembrane" amino acids 6 to 21 (16 residues), see Phobius details amino acids 34 to 51 (18 residues), see Phobius details amino acids 72 to 93 (22 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 193 to 212 (20 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 280 to 306 (27 residues), see Phobius details amino acids 326 to 352 (27 residues), see Phobius details amino acids 379 to 398 (20 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details amino acids 436 to 458 (23 residues), see Phobius details amino acids 463 to 484 (22 residues), see Phobius details amino acids 505 to 524 (20 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 34 to 444 (411 residues), 302.2 bits, see alignment E=3.3e-94 PF00474: SSF" amino acids 34 to 433 (400 residues), 182.3 bits, see alignment E=7.7e-58

Best Hits

Swiss-Prot: 46% identical to YIDK_ECOLI: Uncharacterized symporter YidK (yidK) from Escherichia coli (strain K12)

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 74% identity to cao:Celal_0453)

Predicted SEED Role

"Sodium/myo-inositol cotransporter" in subsystem Inositol catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G331 at UniProt or InterPro

Protein Sequence (527 amino acids)

>Echvi_3497 transporter, SSS family (Echinicola vietnamensis KMM 6221, DSM 17526)
MNITILTFIAFTLLVAVYAWLKTRKENLDSEDGYFLGGRSLTGVVIAGSMIMTNISTEHL
VGMNGSSYKNGFVIVAWEVTSALALIVAAVYFVPRYLKMGLTTVPQYLENRFDAGTRSLV
AFFLLISFAVTLLPIVLYTGAINLESLFNISDTLNISQEQGLWYTVLAVGGIGSIYAIFG
GLKAVAVSDTINGYGLLLAGLMVPVIALFMIGDNNPLLGLERVFENSPEKFNVVGGKDSV
LPFSTLFTGLIINQLYFWCMNQTIIQRALGAKNLKEAQKGLLYTGALKLLVPFIIVLPGV
IGFYFFGDRLYENQDMVYPELVKKVLPVGLTGVFAAVIMGAVLSTFNSVLNSASTIFSID
IYKRLIRPGASAGQLVKAGKLSATILAITSMVAAPMVANAPEGLFQLLQQLNGIFFIPIA
SIMLAGFFTKWVSPLAAKVALVTGLTFYVLTTFVFDIGIHFVHIWGIEFVLNVLIMYVVS
VAWPMAKPTEKTLISAKINTDKWKYASLVSIILVIITVVIYMLLGNI