Protein Info for Echvi_3468 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Na+/proline symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 570 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 42 to 62 (21 residues), see Phobius details amino acids 74 to 96 (23 residues), see Phobius details amino acids 117 to 141 (25 residues), see Phobius details amino acids 148 to 169 (22 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 229 to 248 (20 residues), see Phobius details amino acids 269 to 296 (28 residues), see Phobius details amino acids 405 to 429 (25 residues), see Phobius details amino acids 453 to 474 (22 residues), see Phobius details amino acids 482 to 504 (23 residues), see Phobius details amino acids 511 to 528 (18 residues), see Phobius details amino acids 543 to 563 (21 residues), see Phobius details PF00474: SSF" amino acids 33 to 295 (263 residues), 93.5 bits, see alignment E=6.9e-31 amino acids 386 to 513 (128 residues), 42.9 bits, see alignment E=1.6e-15

Best Hits

KEGG orthology group: None (inferred from 62% identity to mtt:Ftrac_0141)

Predicted SEED Role

"Sodium iodide symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G0G8 at UniProt or InterPro

Protein Sequence (570 amino acids)

>Echvi_3468 Na+/proline symporter (Echinicola vietnamensis KMM 6221, DSM 17526)
MSYLDWIVLFGTLLAIIGFGIYKTYGSKDMNSYLRGGSEMGWWTIGLSIMATQASAITFL
STPGQAYQDGMRFIQFYFGLPIAMIILSVTFIPIYYKLKVYTAYEFLESRFDLKTRTLAA
FLFLIQRGLAAGITIYGPAIILSTLLNWNLTFTNIFIGLIVIVYTVTGGTKAVSITQKQQ
MTVMMGGMILAGILVYNMLPVSLNDAMHVAGKMGKLNIVSFDFDLGDRYNFWSGITGALF
LFLSYFGTDQSQVQRYLNGRSLRESRMGLIMNGFLKVPMQFVILFIGVLVFVFYQFYQPP
IFFNKVQTERLAESDYNEEFQQLQGQYDEVFEEKNVAIKSLIAAQKEGHAGEVASLQQEI
SSKQQQQEEIRTGVKELITKNDPNAETRDTDYVFMRFVMDYLPKGVVGLLFAVIFSAAMS
STASELNALGATSSVDIYKRSINKGKSERHYTLSSKLLTALWGIFAILFATYATLFENLI
QAVNLLGSLFYGTILGIFLVGFYVKWVKGNAVFLAALVAEAVILLVHWKNGSELLGIPID
IGYLWYNAIGCLLVMGLSAVFQTVKGKPAR