Protein Info for Echvi_3381 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Pregnancy-associated plasma protein-A.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1016 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF05572: Peptidase_M43" amino acids 192 to 336 (145 residues), 70 bits, see alignment E=2.3e-23 TIGR04183: Por secretion system C-terminal sorting domain" amino acids 940 to 1016 (77 residues), 35.6 bits, see alignment 3.5e-13 PF18962: Por_Secre_tail" amino acids 940 to 1015 (76 residues), 37.9 bits, see alignment 1.7e-13

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G3P0 at UniProt or InterPro

Protein Sequence (1016 amino acids)

>Echvi_3381 Pregnancy-associated plasma protein-A. (Echinicola vietnamensis KMM 6221, DSM 17526)
MKRIILILRIGLVLSFLLFINSATLFAQQLLTPSLNTSSQVPLEKCTAPLMEQKQMEALG
IFGSKEYFEAWMEDKIQDRKSANLRTTMDEVRLIPVVVHVIHNGEPLGQGANIPLEQIEA
QIRILNEDYNRTNPDAANTLTAFQPVAANANIQFVLAKQDPRGLPTNGIVRVQGSQSEYD
QSDAPRLSQLSYWNSEEYLNIWVAPLTSINLGYATFPLSDLDGLNFPPTAKETDGVTIDY
EYFGEGGSAINASQGRTTTHEIGHFLGLRHIWGDGGCDVDDFVNDTPDQNGPNSNCQTDR
ATCGNLDMIQNYMDYTPDACMNLFTQGQLERMNVVLANSPRRVSLINNRATQDPQIFAHD
LAIETVIDPKDYICSTTITPQISVYNAGTNSLTSAEVAIRLNGQVLEQKSFSLDLDQGDA
DTLSFASIQVAPSGNNFVAEIVSVNGGADENSTNNTRATSPVIQPNLSLPYTYSSGDFNS
VWTVKNEDEALTWETQPLTLDGQSVEALRLNFYNYETSGATDYLISPQINLAQFPDAQLV
FDMAYARYPQTGLDDQLIIGISTDCGNTFDFINPPYQKSQERLETATASTAEFIPSSQRN
FRTEVVDLSPYADEGNIRIAFITINGFGNNLYLKDIRLNPNQATNYSYTLDELASPSPLP
DGSQENDVIHLTNTGQLAINTLLVDRVLNGFAQSLLTLEDMDIAPGEQVALELPSLLRDE
LNGVEYRFHSPNYDQNASNLQELERYFYQDAATVAVPWRQYFDNLPELDPWVTVNPENGQ
TAWEVVTKDGGQNDNLAVLQTQTNGNTYWLGSPLMDLSNTSRASIFFDRAASGITGNTRL
KVMLSLDGGNTFGQQVAIYEGETLNTITGDSPVNPNTPNEFVKEFVDLSEFTGDGSEKVR
IAFVLENGTENTQPIYLDNIELFLSDNPNPVYPSDGDAVLYPNPATSIFNLAFNLPQRED
VRIQIVSTSGQVAHDVVYPGTLNQTYSFSSELFAKGIFIIKIQSETLSLTKRLIIR