Protein Info for Echvi_3247 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Subtilisin-like serine proteases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 922 PF13365: Trypsin_2" amino acids 100 to 262 (163 residues), 49.4 bits, see alignment E=8.7e-17 PF00082: Peptidase_S8" amino acids 531 to 773 (243 residues), 95.3 bits, see alignment E=4.3e-31

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G2D1 at UniProt or InterPro

Protein Sequence (922 amino acids)

>Echvi_3247 Subtilisin-like serine proteases (Echinicola vietnamensis KMM 6221, DSM 17526)
MVTRWSLMEYVANRYGKVQPVFEEAAKKLQRVKAKEIPLLSLEDDLERVKLRMAREEGEM
PIIMERINGGVDFQDSYILEMLSTLSKAVCRITQHGRPIGTGFLISENVIMTNNHVIDRP
ENAQGMMAEFNYELDSNKNIKKSFSFSLDPDKFFLTSSYTANPEVPYSGLDFTMIAVSEG
SQENVPLSTVKPIYLDGVRGKIIKGESCVIIQHPRGMPKKIVLKNTAFFSETRTRIVYES
DTLPGSSGSMVVALGTGEIIALHHAGLPRTDSQNRILTRSGAIATASTPDEEIDWIGNEG
IKISRIINALKDSALPPGMQAVKERLLHKTTQTQGEINDGRDNREASFNKAPIPVNPEKE
QKPKIAMKSSPTSRQDYIFTAINNPKVLGTIAEILKARYGETPLIKLSMPSFAAVDRVEL
FSLSAPVVGNIEDEARNLSTIPGIINVETDVPLHLNTGKDQKDPDHSIYEGMVEDGYGKF
NEDEFLKKYRHERQSIYVQDKTPQYHRKWNWYATAFDSVLADKQVVSPVDKGIRIIQFDT
GFTDHAKVQGGFDKDLDMDFVDQDDDATDSFTAGILKHPGHATRTGSLLIGNEVTLIEKN
GNSGLLSQFGFQLVPYRICKSVILIRRQQELADALDLCISQRYPIISMSLGLPPTMATAA
MAKKAYDAGVIWCCAAGNVVQVVVAPAVYPGTIAVAASNPMDEEWKGSSRGSTVDITAPG
EDVYVPIFLEPESNGTPGESFAYGNGTSYATPHVAAAAALWLAKYDDTLSNGEYAGWRKV
EAFRKAVDVSARRKNRLPRVGFGHGILDVEKLLKTPPVAPVQLEYAYKNTDQGRLGEVTQ
AYGEMAKTLWNKIHGWAFGIPRGGQEAYAPDSRELSDYAKMLERTLINESTTSLESGDDV
SQETLLELFSKVHQKIESELKK