Protein Info for Echvi_3213 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02321: OEP" amino acids 23 to 182 (160 residues), 63.5 bits, see alignment E=1.2e-21 amino acids 227 to 411 (185 residues), 87.6 bits, see alignment E=4.8e-29

Best Hits

KEGG orthology group: None (inferred from 55% identity to mtt:Ftrac_1542)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1N2 at UniProt or InterPro

Protein Sequence (415 amino acids)

>Echvi_3213 Outer membrane protein (Echinicola vietnamensis KMM 6221, DSM 17526)
MKIIVNIVILVFLGTSVSQAQVLDDYFKIAAENNPGLQAKYREFEAAIQKVEQVNTLPDP
NFSFGYFISPVETRVGPQKARFSLTQMFPWFGTLRAQGNAAALMAEAKYQAFLDARNRLY
YQVAAAYYPLYELNQWKEIERENIEILESYKTITNKKFENGVGTMVDFLRVDIMLKDATT
NLSILNDKEAPLLTRFNKLLNREEDALVTVEDSLVAQALPDNFRKDSLLTNNPVLEELDL
KIASSEASEEVAYKQGLPKFGLGLDYVLVGERTDLASDMAAPQGNGKNAMMPMVSVSIPI
FRSKYKAAVKEAQLMQESYSLQKEDFANTLTSSYEMAWFEIQQQQELIDLYDQQIQESIQ
ALNLLFTAYSNSGNEFEEVLRMQQQLLKYEKMKATAETQYQIALAKLNYLTAKTY