Protein Info for Echvi_3127 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1068 transmembrane" amino acids 15 to 32 (18 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 125 to 1066 (942 residues), 761.3 bits, see alignment E=2e-232 PF13715: CarbopepD_reg_2" amino acids 126 to 206 (81 residues), 74.4 bits, see alignment 9e-25 PF13620: CarboxypepD_reg" amino acids 126 to 194 (69 residues), 50 bits, see alignment 4.8e-17 PF07715: Plug" amino acids 214 to 319 (106 residues), 59.7 bits, see alignment E=5.5e-20 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 295 to 324 (30 residues), 59.4 bits, see alignment (E = 2.2e-20)

Best Hits

KEGG orthology group: None (inferred from 68% identity to shg:Sph21_1871)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G3D6 at UniProt or InterPro

Protein Sequence (1068 amino acids)

>Echvi_3127 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MYSTILKQSIFLSKRLVYVFVVQLFMMQLLLANTSNGQNKGQIMISFFSQEAPYTDVFNQ
IEAQTDLVFLYDDDISGSDKRFTLNRENISLNELLGLLEKKGLKFMREGDHISVKMAENA
YDKIDITGRVTDENGAPMPGATILIKGTNVGTVTDNDGYYRIHAEEKGVLIFSMLGYQNQ
EVNIDNRSTVNVSLKEESTALDEVVVMGYNSVEKQHVASSIAELDMKRAKMRPIFKLQEA
FSGTLPGVTMLQGSNLPGSVPGTINIRGISTLQNADPLVIVDGMEQSLTDIDPNEIKSIS
VLKDAASAAMYGSRGANGVIIITTNRGTTGQFRVDLHSWAAVNDPIDMPTFVNSADYMRL
NNEAREFQGQTPQFTDEEITNATNGNTTNTDWLDEVMERRAHSYNMSANISGGGGVGTFN
LMLGYLKENGLNTYEGSERFSARFNTDIHIDDKFVLLADFYARRLQVNRLQANSDGHGLY
KIAWRMNPTQAVFYDSDLPDHYILHNEMNPIASINHGGERNNLYDRSTINLRPRYHINDN
LHINGNISYMINKSANKYKRETFKFFDGDGIPVATWANDVDSEQGVSVSQLTARANINYE
RDLRKEQDKLYLVAGTEIMNYNYTDYREIAKASFYSKLNYSFDDRYLLEVTARGDGSSKF
APGHRWGFFPSGALAWNIHNERFLSGVTQSGLINNMKIRLSYGLIGNENVNPYLWQEVVN
NWGWTMRIPNPSFSWEKQRQANIGIDLGMFDNRFKFTAEFYRKHSFDLIYSEFPVPPLTG
SNSLESAVNIGEVENKGWELSGSWSDQVGELSYTIGGILFENNNKVLKAGYNKSDTLIFK
DNNEKIWYRGIALDNYYGFESDGYFQNQQEVDETSAKLPNTLPGDIRYVDQNGDGVINDK
DRVDLGDPFPHMNYSITLDLRFRHWDFSFLGHGVGRRTGRLGGQEGFPVFMDGENNDLGA
PRQYYMDNRWTPETPNSRFPRVWTGTTPNSELSDVWLSNASFFRIKTLQLGYTFPHITKG
VKNMRVYINAQDAFTFTNWEGLEPERNGGTGNYPRMASYSLGVKFTIL