Protein Info for Echvi_3122 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Metal-dependent amidase/aminoacylase/carboxypeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 PF01546: Peptidase_M20" amino acids 133 to 459 (327 residues), 92 bits, see alignment E=2.5e-30

Best Hits

Predicted SEED Role

"Peptidase M20D, amidohydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G3D2 at UniProt or InterPro

Protein Sequence (465 amino acids)

>Echvi_3122 Metal-dependent amidase/aminoacylase/carboxypeptidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MTLSHMCQEPKVPLLHLRAIKTGKRTTQIFKQINYLVIGTCFLWGAVCPAQEKKAPDGIH
KAIQARTDAIFDSLVLVRRDLHRHPEISGQEKRTAEFVTNYLLALGLEVKVGVGGYGVVG
ILKGKQGGKKIAWRADMDALKFDAQDPEVFGSIHKGINHYCGHDVHVTIALGMANVLAHH
REQIKGTVYFIFQPSEENYKGAKSMISDGLFEGIAPEEMYAAHISPMPSGLVASKPGYLF
ADYKEIHVTYEASAADEEVIAFTKNLLSGLQNVPASSEFWDTQNLMDPTIGIGNPETIFQ
DYITVKENVTVSRQDGQVRISGILSASSASLMDAIPRRLQRSIDQSDFADRFMDIAFATE
GFLYSTQRANIQNNSSLTEQAIQGIAGIYGQGSAIPLYGVIPDGRGDDFAYFQEKVPGVY
FLLGGSNFEKGIIAMPHTPHFRVDETCIKSGVNYFSSLLIERTNN