Protein Info for Echvi_3087 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Pectin methylesterase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01051, pectinesterase [EC: 3.1.1.11] (inferred from 42% identity to psn:Pedsa_0465)Predicted SEED Role
No annotation
MetaCyc Pathways
- pectin degradation II (4/5 steps found)
- pectin degradation I (1/3 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.1.1.11
Use Curated BLAST to search for 3.1.1.11
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G3A2 at UniProt or InterPro
Protein Sequence (357 amino acids)
>Echvi_3087 Pectin methylesterase (Echinicola vietnamensis KMM 6221, DSM 17526) MIDVRKAKGLMKTGLLLLLLPPISCSGSEEMTPEKDTATGDITYDFIVDQKGSGDFLSVQ EAIDAARSFQQDHQYILVKNGTYQEEIEIPKGKDNLVLIGETKGEVVLTFDNAAEKIDEE TGAPFGTSGSASTYIHGEGFVAVNMTFENSAGTEHGPGLAVYVNSDRALFYHCSFLGRQD TFYGNRKRMFLKNCYLEGTVDFIFGPVTAVFENCEIHSYGGTSITAASTESYVDYGLVFR ECTLTAESGVKTDLGRPWRPYAAVAYIQCEMGGFIKPAGWNNWGNSDNEQTARFVEYGNT GAGATTTQRVSWSRQLDEDEVGAYETLEVLQSTYAENKVTDNWDPYVLLEDLSELIK