Protein Info for Echvi_3016 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: K+ transport systems, NAD-binding component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 PF02254: TrkA_N" amino acids 5 to 125 (121 residues), 90.4 bits, see alignment E=2.1e-29 amino acids 235 to 349 (115 residues), 72.3 bits, see alignment E=8.7e-24 PF02080: TrkA_C" amino acids 164 to 223 (60 residues), 40.3 bits, see alignment E=4.7e-14 amino acids 382 to 447 (66 residues), 37.9 bits, see alignment E=2.6e-13

Best Hits

KEGG orthology group: K03499, trk system potassium uptake protein TrkA (inferred from 43% identity to fbc:FB2170_16766)

Predicted SEED Role

"Trk system potassium uptake protein TrkA" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZ96 at UniProt or InterPro

Protein Sequence (448 amino acids)

>Echvi_3016 K+ transport systems, NAD-binding component (Echinicola vietnamensis KMM 6221, DSM 17526)
MAMNIVIAGAGDMGFHLAESLSYENKDITLIDTDKDILEHVASRLDVLTVMGDSASIDVL
KNANVKDANMVMAVTTSEKTNIVTAMLAKQLGAKRVIARVRNHDYLLEENVAYFHNLGID
DIISPTMLCSGEIHRMVKNSTFSDIFEFEEGKINVMGVILDQFSSLVNKRLSDTRTMSIF
EDVRIIAIVRDQMTIIPGGNTMLRNNDHVYFVSNKKASESIAQLTAQREIDIKNVMIIGG
DDLAFTSALKLEPEYKVTLIHNDKERCKWLSERLHSTLVINGDYKNIELLIEEGLEEMQA
FLALTESSETNIITSLSAKNHGVYKTIAHVDTREYIHISHSIGVDSLINKKLVAANQIAR
HLRKGKVEAISGIYGVDAEFIQYVISKNNRLTKKQLRELHFPETAIVAGVIRGDAVFIPD
GDFKLQLNDKAIVLALPSAKSSLEKLFN