Protein Info for Echvi_3007 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Thiol-disulfide isomerase and thioredoxins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 286 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 65 to 85 (21 residues), see Phobius details amino acids 91 to 110 (20 residues), see Phobius details amino acids 117 to 138 (22 residues), see Phobius details PF08534: Redoxin" amino acids 158 to 275 (118 residues), 43.6 bits, see alignment E=4.1e-15 PF00578: AhpC-TSA" amino acids 158 to 271 (114 residues), 46.3 bits, see alignment E=6e-16 PF13905: Thioredoxin_8" amino acids 176 to 269 (94 residues), 32 bits, see alignment E=2e-11

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G322 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Echvi_3007 Thiol-disulfide isomerase and thioredoxins (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKTVSSIFLAAIIFLISFYSSAYVLTLSRDFNLWGFGALLGFMLILAIDALVIRQLSNL
IPSKWVISASLFGILLFAFISLPSLRFAIKVLPTFICLVLGSLAAAIMTAKTIKNRYTYG
FSLFLFPFVLNLSVYDTWVHYIEFGNTSGQVTEETSVSFKATDEKGHEITNEQLKGKVVL
LDFWFIGCAPCWKKFPDLQQLHEQYLDHPDLAIYAMNRPMSSDRPGQAFEAIRDKGYTFN
VLQGTQKIMDDFGVYVYPTVVVLNKEGSVVYMGSLDRAQDIIESLL