Protein Info for Echvi_2996 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 TIGR03705: polyphosphate kinase 1" amino acids 23 to 698 (676 residues), 716.8 bits, see alignment E=1.4e-219 PF13089: PP_kinase_N" amino acids 24 to 128 (105 residues), 84.1 bits, see alignment E=2.4e-27 PF02503: PP_kinase" amino acids 138 to 321 (184 residues), 161.8 bits, see alignment E=4.4e-51 PF17941: PP_kinase_C_1" amino acids 350 to 514 (165 residues), 232.8 bits, see alignment E=5e-73 PF13091: PLDc_2" amino acids 387 to 508 (122 residues), 35.2 bits, see alignment E=3e-12 PF13090: PP_kinase_C" amino acids 522 to 686 (165 residues), 209.7 bits, see alignment E=6.6e-66

Best Hits

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 63% identity to mtt:Ftrac_0301)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZ76 at UniProt or InterPro

Protein Sequence (711 amino acids)

>Echvi_2996 polyphosphate kinase 1 (Echinicola vietnamensis KMM 6221, DSM 17526)
MEQHTMETSERDRIDIKIQSSDLISRDLSWIKFNYRVLDQSQKLSRTIFEKLKFLAITAS
NLDEFFMIRVGSLYNYLDYDKERIDYSGLREDPFKAKLMDDAQGFHFAQHEHFLHEILPK
TKASGFELSNVQNLSNDEQEIIKEYFYKAVYPMLTPMVFDGYHTFPILMNKLLIFGVVTI
NPGDKKDNRKLSFVQIPSNIPRFFEIEREDEMVYVPIEEVIREHIVSLFRNVIIESINLF
RIIRNGDFTLEETEDMDSNFLEEVKRKLNERKTGRVVRVEVEEGYSKWMMNLLKDRWNLQ
NDSVFKIRKESMLDFTCFWQIIGDKRFKDRIPQPPMQVPPLSYPLTGSQDVFQVLKQKDV
LLHHPYNSMEPIMDLLHKAAEDPSVMAIKMTIYRLAKHSRITQALLKAAENGKHVSVLFE
VKARFDEENNMQEAKRLQKAGCFVIYGVSNFKTHTKLLLIVKKDENKVTRFVHLGSGNYN
EDTSKLYTDLGLLTTNEVLANDVSEFFNVITGHSMPSNYKNLITAPQGMRKQLIEFVEHE
AENAKRGLPCGIVIKVNSLEDSETIYALYRASQSGVPIKLIVRGICCLRPGRKGLSENIE
VYSIVGDFLEHSRIYHFHNNGDSRTYVGSADMMVRSFEKRLESLFRVQDPFLEKQLMNIL
AYNLRDNVNAYIMQEDGSYLAKSPEEGESEFNIHKEFYRVTPDIVENVSLL