Protein Info for Echvi_2982 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Phosphomannomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 47 to 185 (139 residues), 137.3 bits, E=4.2e-44
• PF02879: PGM_PMM_II
  • amino acids 209 to 314 (106 residues), 85 bits, E=7.1e-28
• PF02880: PGM_PMM_III
  • amino acids 323 to 448 (126 residues), 68 bits, E=1.2e-22

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 57% identity to chu:CHU_0998)

Predicted SEED Role

No annotation

MetaCyc Pathways

• colanic acid building blocks biosynthesis (9/11 steps found)
• GDP-mannose biosynthesis (3/4 steps found)
• β-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation (2/3 steps found)
• superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis (8/14 steps found)
• β-(1,4)-mannan degradation (2/7 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 5.4.2.8

Use Curated BLAST to search for 5.4.2.8

Sequence Analysis Tools

See L0G301 at UniProt or InterPro

Protein Sequence (575 amino acids)

>Echvi_2982 Phosphomannomutase (Echinicola vietnamensis KMM 6221, DSM 17526)
MTDTSIITKAQSWLNSNIDQESKTKIQQLLDASDSSELVDAFYKDLEFGTGGLRGVMGIG
SNRMNVYTVGMATQGLANYLLACFPGEDIKVAITHDSRINNTLFAETTANVLTANGIKVK
YFEEMRPTPMLSYAIRHYGCKSGVMITASHNPKEYNGYKAYWEDGGQIVAPHDKNIIMEV
QKIKSIDDVKWDKNDALIEYIGAEMDLTYLNDIKKFSLSPKAILNQRDMCIVFSPIHGAS
GKMVPAALKTFGFENIHVVKEQEAPDGTFPTVVYPNPEEAEALSLSLKLAKEVNAELVLA
CDPDGDRYAAAIPNEKGEYELLNGNQTGSILTYYLLNQWREHGLFTGDQFMVNTIVTTEL
IEEICHGFNIPCYRVLTGFKNIAAIIRELEGKKQFVGGGEESYGFLVGDAVRDKDGVSAC
AMLAEVVAYYKEKGMTLFDVLAEIYQSYGFYKESLISVTKKGKDGAEQIQQLMHGFRTNR
PEAINGTKVVKVVDVKESKVYNIADGTEEDLDLDKSNVIQFYLEDGSKISARPSGTEPKI
KYYISVNESLPNRDAYRKVEASLAQKIEGLKKFFE