Protein Info for Echvi_2910 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Peroxiredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 152 PF08534: Redoxin" amino acids 5 to 131 (127 residues), 53.8 bits, see alignment E=1.9e-18 PF00578: AhpC-TSA" amino acids 7 to 128 (122 residues), 109 bits, see alignment E=1.5e-35

Best Hits

KEGG orthology group: K03564, peroxiredoxin Q/BCP [EC: 1.11.1.15] (inferred from 55% identity to mtt:Ftrac_1545)

Predicted SEED Role

"Thiol peroxidase, Bcp-type (EC 1.11.1.15)" in subsystem Thioredoxin-disulfide reductase (EC 1.11.1.15)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1H2 at UniProt or InterPro

Protein Sequence (152 amino acids)

>Echvi_2910 Peroxiredoxin (Echinicola vietnamensis KMM 6221, DSM 17526)
MALQKNTKAPDFSLPSTSGDLFKLSENFKGKSALIFFYPKDQTKGCTQEVCSFRDNFSVF
SSLEIPIVGISRDSIASHQEFKKMHRLPFELLCDEDGSVCKQYKALMPLIKMPKRITYLL
NAQHEIVAVHEGLFDGPAHVKAMMEEVKALEK