Protein Info for Echvi_2887 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Cytochrome c, mono- and diheme variants
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 42% identity to sli:Slin_3560)Predicted SEED Role
"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)
MetaCyc Pathways
- aerobic respiration I (cytochrome c) (3/4 steps found)
- arsenite to oxygen electron transfer (1/2 steps found)
- aerobic respiration II (cytochrome c) (yeast) (2/4 steps found)
- arsenite to oxygen electron transfer (via azurin) (1/3 steps found)
- Fe(II) oxidation (2/6 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.9.3.1
Use Curated BLAST to search for 1.9.3.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0G2C2 at UniProt or InterPro
Protein Sequence (313 amino acids)
>Echvi_2887 Cytochrome c, mono- and diheme variants (Echinicola vietnamensis KMM 6221, DSM 17526) MKKNKAVLLTTFMGLASSTAFAQNVEEPSFWSALGTMNSSELMLLLMIIVMLGVLVLLLL LMIYLMSFMVTLLKRENPALANQPSWWEQFNERFVSGKLKPVEEEGEIMLSHNYDGIREL DNFMPPWLTYLFYGSTIFAIFYLINYSAIGWGKTPEEEYQAQLKAEEIAAEKRKELALAS IDESNVEFDQSEFVLTAGGTIYQNNCVACHAADGGGGVGPNFTDQYWLHGGSIQDVFKTV KYGVPDKGMIPWQDQLSPEEIMQVSNYILSLQGKTPANPKEPQGELYVPDNEEGETDAAD STGVQPDSVKVDV