Protein Info for Echvi_2885 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: cytochrome c oxidase, cbb3-type, subunit I/cytochrome c oxidase, cbb3-type, subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 717 transmembrane" amino acids 19 to 43 (25 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 131 to 152 (22 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 206 to 228 (23 residues), see Phobius details amino acids 238 to 256 (19 residues), see Phobius details amino acids 269 to 296 (28 residues), see Phobius details amino acids 308 to 324 (17 residues), see Phobius details amino acids 344 to 366 (23 residues), see Phobius details amino acids 386 to 409 (24 residues), see Phobius details amino acids 436 to 457 (22 residues), see Phobius details amino acids 497 to 520 (24 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 10 to 474 (465 residues), 655.1 bits, see alignment E=7.1e-201 PF00115: COX1" amino acids 14 to 445 (432 residues), 392.1 bits, see alignment E=3.3e-121 TIGR00781: cytochrome c oxidase, cbb3-type, subunit II" amino acids 489 to 704 (216 residues), 250 bits, see alignment E=2.4e-78 PF02433: FixO" amino acids 489 to 703 (215 residues), 321.6 bits, see alignment E=2.4e-100

Best Hits

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] K00405, cb-type cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 78% identity to mtt:Ftrac_1616)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) / Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYY7 at UniProt or InterPro

Protein Sequence (717 amino acids)

>Echvi_2885 cytochrome c oxidase, cbb3-type, subunit I/cytochrome c oxidase, cbb3-type, subunit II (Echinicola vietnamensis KMM 6221, DSM 17526)
MSEPLLEKFSYDNKIVKYFGAATIIWGVVGMLVGILAATQLFLPEANLGNPYTTFGRIRP
LHTNAVIFAFVGNAIFAGVYYSMPRLLKARMWSDTLSWINFWGWQLIILAAAITLPLGLT
TSKEYAELEWPIDIAIAVVWVAFGANMIGTLIKRRERHMYVAIWFYLASFVTVAVLHIFN
SLELPVSLFKSYSAYAGVQDALVQWWYGHNAVAFFLTTPYLGLMYYYLPKAANRPIYSYK
LSIIHFWALIFIYIWAGPHHLLYTALPNWAQVLGVAFSIMLIAPSWGGMVNGLLTLRGAW
DKVRVDPVLKFMVVAVTAYGMATFEGPLLSLKSVNAIAHYTDWIVAHVHIGGLGWNGFLT
FGMLYWLCPRMWNTKLYSTKLANTHFWLGTLGIIFYALPMYVAALTQSLMWKEFNEMGRL
AYPNFLETTLQIVPMYMFRAFGGVLYLSGTLIMIYNLVKTTKMGAFVAEEPDEAPALTKP
VAQKGEYWHHVWERKPIFFTILATVAILIGGAIEIIPTILVKSNVPTISSVTPYTPLELQ
GRDIYIKNGCVGCHSQMIRPFRSETERYGEYSKAGEFVYDRPFLWGSKRTGPDLHRVGGK
YPDSWHYHHMLDPRTMSPGSTMPPYDWMITTTMDHEDLPAKIRTLQKLGVPYPEGYADGP
AMEDLNEQANKITAGLKDANIEVLPNTEIVALIAYLQRLGTDIKKLDAPTKTANEAK