Protein Info for Echvi_2695 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-galactosidase/beta-glucuronidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 983 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 45 to 151 (107 residues), 31 bits, see alignment E=1.1e-10 PF13364: BetaGal_ABD2" amino acids 46 to 148 (103 residues), 22.7 bits, see alignment E=6.5e-08 PF22666: Glyco_hydro_2_N2" amino acids 78 to 164 (87 residues), 37 bits, see alignment E=1.7e-12 PF00703: Glyco_hydro_2" amino acids 208 to 309 (102 residues), 54.1 bits, see alignment E=1.1e-17 PF02836: Glyco_hydro_2_C" amino acids 313 to 450 (138 residues), 21.2 bits, see alignment E=6.4e-08 PF16355: DUF4982" amino acids 620 to 677 (58 residues), 58.1 bits, see alignment 2.9e-19 PF18565: Glyco_hydro2_C5" amino acids 700 to 793 (94 residues), 64.5 bits, see alignment E=3.4e-21 PF00754: F5_F8_type_C" amino acids 846 to 942 (97 residues), 29.6 bits, see alignment E=3e-10

Best Hits

KEGG orthology group: None (inferred from 61% identity to bth:BT_2680)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G250 at UniProt or InterPro

Protein Sequence (983 amino acids)

>Echvi_2695 Beta-galactosidase/beta-glucuronidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKIKYLLLLGTFLLFHSTKAQRTTYNFNSGWKVKTGDPSLAEKPSYDDSRWKAVTLPYAW
NEDEAYKVDIHSLTTGIAWYRKTFVLPEGQEDQKVFLEFEGVRQGGEFYVNGTHIGRHEN
GAMAVGFDISDLLNPFPESNVVAVRTDNDWDYREKATQTKYQWSDRNFNVNYGGIPKNVY
LHITDKLYQTLPLYSNLGTEGTYVYAQDIDVDNGTARVTAESQVRNEQKRALEVQYQVTI
KEQDGTLVKKIEGSKKTISPGQTTMLSATAELDHLHFWSWGYGYLYDVFTTLLVDGKEID
EVKTTTGFRKTAFKDGMVYLNDRVLQVKGYAQRTSNEWPGVGMSVPAWISDYSNRMMVEG
NANLVRWMHITPWKQDVESCDRVGLIQAMPAGDAESDVQGFRWEQRKNLMRDAIIYNRNN
PSILFYECGNDNISEEHMAEMKQIRDQHDPHGGRAIGSREMLGSKEAEYGGEMLYINKSA
DQPMWATEYSRDEGLRKYWDEYTPPYHKDGDGPPYKGKDASEYNRNQDSHAIEDIVRWYD
YYRERPGTGKRVSSGGVNIIFSDTQTHFRGAENYRRSGEVDPMRVPKDGYFAHQVMWDGW
VDPEQPRTHIMGHWNYEAGIKKPIYVVSNAAEVELFVNGKSLGKGEQSYRFLFTFPEVTW
EPGAIKAVSYNELGEAVSEDEIVTSGKPAALKLSLKQAPGGMVADGHDLGLIQVEVVDSE
GDRCPTALDMVHFELKGAAEWRGGIAQGPEDNFVLSKKLPVEGGVNRVFVRATDAPGKIT
ITAKAEGLKPATLSWSTQPFEVTGGLSTALPGENLESFLGRGPTPKGPSYRVTRTPVGIQ
SAKAQSNPEDVSKSFDDNEMTSWENDGERSTGWIEYELEREAEISEITMKLSNWRNRSYP
ISISMDGKEVFSGNTPKSLGYVTLQFPPTRSKKVLIKLIGANIDGDAFGIVEITGKIEPS
GAEKKSKGELDIVEIEFYERNHQ