Protein Info for Echvi_2677 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-1,4-xylanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00331: Glyco_hydro_10
  • amino acids 30 to 363 (334 residues), 323.3 bits, E=8.2e-101

Best Hits

Swiss-Prot: 41% identical to XYNA_BACOV: Endo-1,4-beta-xylanase A (xylI) from Bacteroides ovatus

KEGG orthology group: K01181, endo-1,4-beta-xylanase [EC: 3.2.1.8] (inferred from 43% identity to ttu:TERTU_0736)

Predicted SEED Role

"Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Xylose utilization (EC 3.2.1.8)

MetaCyc Pathways

• (1,4)-β-D-xylan degradation (2/2 steps found)
• cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.8

Use Curated BLAST to search for 3.2.1.8

Sequence Analysis Tools

See L0G036 at UniProt or InterPro

Protein Sequence (379 amino acids)

>Echvi_2677 Beta-1,4-xylanase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKLFIIPVVLFGLWSCVFPLSRDQQAQSGLKDLFYDDFYIGAALSGNDVREQPTSMVMTL
SNHFNSLSPENLMKWQSIHPDSGKFQFVQADRYVELGKRLGCHLVGHTLVWHKQTPEWVF
KDQGGMPRSSKDLSAMMQDHIQNVMGHFKGSVKTWDVVNEAFTDEGDFRPSAWYQTLGED
FIKLAFQTANEADPEAELYYNDYNVWKPKKTDAILSYTSKIRNQGVNIHGIGMQCHLGLE
YPTVNQLEVAIQKIIKHGFRISITELDIDVLPNQSGRQGADIDANFPYEAKYDPYKDGLP
PMMQEKLTQRYREIFKLFLKYRKHIDRVTFWSIRDQDSWLNNWPIRGRTAYPLLFDEEYQ
LKDYIFDSLTTLKKGDNSG