Protein Info for Echvi_2663 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Beta-1,4-xylanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00331: Glyco_hydro_10
  • amino acids 42 to 380 (339 residues), 343.4 bits, E=6.1e-107

Best Hits

Swiss-Prot: 60% identical to XYNA_BACOV: Endo-1,4-beta-xylanase A (xylI) from Bacteroides ovatus

KEGG orthology group: K01181, endo-1,4-beta-xylanase [EC: 3.2.1.8] (inferred from 63% identity to zpr:ZPR_0754)

Predicted SEED Role

"Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Xylose utilization (EC 3.2.1.8)

MetaCyc Pathways

• (1,4)-β-D-xylan degradation (2/2 steps found)
• cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.8

Use Curated BLAST to search for 3.2.1.8

Sequence Analysis Tools

See L0G0S0 at UniProt or InterPro

Protein Sequence (386 amino acids)

>Echvi_2663 Beta-1,4-xylanase (Echinicola vietnamensis KMM 6221, DSM 17526)
MTMSRTKRMAGVFQTSIKCLLASALLFSACKGNAQHEENSTLKTAFEDKFAIGTAMNAWQ
ISGRDSAATKIIKDQFSAIVAENCMKSGRLQPEEGEFTFDLADQFVEFGEQNDMLINGHT
LIWHSQAPRWFFTDAEGQDVSREVLIERMKTHIHTVVGRYKGRVDTWDVVNEAILDDGSY
RESKFYQIIGEDFIKLAFQFTHEADPDAELYYNDYSMAEPGKREGVVRMVKKLQAEGVKI
DGIGMQGHIGLHHPEIREFEKSLEAFADLGVEVMVTELDLTVLPSPWDDQGAEVSKNFDY
EDKMNPFPNGLPDEVRDAFDARYLEFFALFLKHQDKISRVTLWGVADQHSWRNGWPIRGR
TDYPLLFDRENKAKPIVEKLIKLTKQ