Protein Info for Echvi_2587 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1176 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 134 to 1176 (1043 residues), 880.6 bits, see alignment E=1.8e-268 PF13620: CarboxypepD_reg" amino acids 134 to 204 (71 residues), 48.2 bits, see alignment 2.3e-16 PF13715: CarbopepD_reg_2" amino acids 135 to 215 (81 residues), 72.1 bits, see alignment 6.3e-24 PF07715: Plug" amino acids 223 to 328 (106 residues), 62.9 bits, see alignment E=7.4e-21 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 304 to 334 (31 residues), 58.5 bits, see alignment (E = 4.2e-20) PF00593: TonB_dep_Rec" amino acids 538 to 1126 (589 residues), 40.3 bits, see alignment E=7.8e-14

Best Hits

KEGG orthology group: None (inferred from 46% identity to phe:Phep_2990)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FY35 at UniProt or InterPro

Protein Sequence (1176 amino acids)

>Echvi_2587 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKILHAIRMISKYTLIGFVFQLAFLNLLHAGPSKAQGNLDMEKVTVNVKATAAPLPSVL
ESIKSQTDFVFIYDDKIIPSNTEISIEARNEPLENVLLTLSKEHRWAFKQVNDRISIKPI
KGLHLGKIVIREVTVSGTVMDANNQPIPGVTVLVKGTTNGTTTDLDGRYRMNVPENSVLV
FSFVGFVSQEVAVGNKDVIDVQLEEKISALNEVVVVGYGEQKKINLTGAVNQVGSEVTEN
RPAPNLTRMLQGTLPNLNIKMVDGSPTRSAAFNIRGMTSIGAGGDALVLIDGVEGDPNLV
NPNDVESVTILKDASSAAVYGSRAAFGVVLITTKSAKAGKSQLNVNLNHSVNKRTVVPDL
VNNGYQWAKNFDEAFYGWYDYKTHPISVNSTFPFSLEYLDRLRQHDEDPSLPKVEYVEEV
GRYEYYGNTDWFKYHHKDNMPATEASISASGGNENARYFISGMYYHQDGIFNYSSDKFDK
YNLRAKGEVNLNDWLVLENNFDLSTYTYGYPLLANGDINIWRYLAVQSYPMLLMNNPDGT
YSQNGVYVGASFLEGNSRSDQSNFFVRNTPTLTATPFGDLLTLKANFTFSKKFIKDKRVN
NYVNYSNAPGDLNRFGNSLLRQYEDETTYWGSNITAQFNKTLNEEHDLGLLLGYNIESSL
TENWNTSRDGLLVPGKPDYNLLDGLNYTIRGGGSEWKYLGAFYRLNYSYKDKYLLEFNGR
YDGSSKFPSDERYGFFPSVSAGWNVSEEGFMQNTRNWLANLKIRSSYGSLGNGNVAPYRY
LETMSVNKSSVMLEGIQKGYTSLPGVIPAGLTWERATTFNIGVDASFLDGRLGVNYDWYN
RMTTDMFTYGQPLPNVFGATEPYGNYADLSTKGWEFTLTWKDQAIVGGKPFTYGFNGSLW
DNRSTITKFNNPEKVLGSGYYVGQNVGEIWGYVTEGLFTSEEEVLNHADQDFLRNSNGNI
WLPGDIKFADLNDDGVINQGDNTVNNPGDRKVIGNNTPRYQFGFTLNANWNNFGISAFFQ
GIAKRDWYFAPEADLFWGIYNRPYSFQPTKMMNDYWTEENPDAYFPRLRGYTALGTGRSL
GAPQTRYLQDASYIRLKNITVDYTLPTQWVNKIGMQRAKIFFTGQNIWTRTGLSKHTDNF
DPEIIENPLGDMTNGYGQGDAYPMLKSYTLGVNLSF