Protein Info for Echvi_2585 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Fe2+-dicitrate sensor, membrane component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 transmembrane" amino acids 96 to 116 (21 residues), see Phobius details PF04773: FecR" amino acids 133 to 226 (94 residues), 52.3 bits, see alignment E=6.5e-18 PF16344: FecR_C" amino acids 272 to 338 (67 residues), 66 bits, see alignment E=2.4e-22

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZU2 at UniProt or InterPro

Protein Sequence (342 amino acids)

>Echvi_2585 Fe2+-dicitrate sensor, membrane component (Echinicola vietnamensis KMM 6221, DSM 17526)
MMEHNNVNIPKEVTRLIGKLLSGIPLGAEELDHLNQWYDECYDSEWETADQDLGPDMLKR
IHDKIDKGNGGRVSSDATYPRTVSAHKRFTGYKTQIWLRAAVVTFLLMATVLTIYVSQYG
KQEVPQTVAAWTTYQNPAGQKSKVRLPDGSVVYVNAATEIKYQDGFGETHRELFLNGESY
FEVAKDSLPFRVHSAGLVTQALGTSFNISTFDAASIRVQLASGIVKVYHAFKDQPSVQLS
PGEEVRLEDGQLSSVFSFHIDQAIAWKEGKIWLDKTPLREVVPMLERWYDVDITVTNPPQ
DEVRFTGEFKNAMLSHLLESLAYSYRFEYKINKKNITITFND