Protein Info for Echvi_2572 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Zn-dependent oligopeptidases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 676 PF01432: Peptidase_M3" amino acids 225 to 674 (450 residues), 457 bits, see alignment E=1.1e-140

Best Hits

Swiss-Prot: 37% identical to DCP_SALTY: Dipeptidyl carboxypeptidase (dcp) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01284, peptidyl-dipeptidase Dcp [EC: 3.4.15.5] (inferred from 62% identity to mtt:Ftrac_2370)

Predicted SEED Role

"Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5)" in subsystem Protein degradation (EC 3.4.15.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FY21 at UniProt or InterPro

Protein Sequence (676 amino acids)

>Echvi_2572 Zn-dependent oligopeptidases (Echinicola vietnamensis KMM 6221, DSM 17526)
MNPLLEKFNTPYDTAPFDKIKNEDFLPAIEEAIQEAKAEIATIKATETPTFSTVIEALDR
SGERLDIVSSIFFNLNAAETNDDIQKLAREISPILTAYSNDILLDQELFALVDEVYQQKA
VLDLDEEQETLLDKTYKSFVRNGANLSEEDKQKLREIDKELSQKSLAFGENVLAETNKYE
LVVENEEDLSGLPEGIKEAAAQTAADKGKEGKWVFTLAFPSYVPFMTYADNRALRQELFM
AYNTKSCKGDELDNQQIVKEILDLKNQRANLLGYPRYADFVLEERMAKSAPEVQKFLGDL
LEKARPKAQEELEELTAFAQQQGGPEVLQKWDFGYYSEKLKKAKFEVDDELTKPYFELEN
TIQGVFKTAAKLYDLEFIKNEAIPVYHEEVVAYEVKDANSGKHLAVFYADFFPRAGKRNG
AWMTVYRGQSKIDGEDKRPHISIVCNFSRPTKSTPSLLTFNEVTTLFHEFGHALHGMLAN
GTYSSLSGANVYWDFVELPSQIFENWCYEKECLDLFASHYKTGEKIPEALVQRIRKAANF
HQGYQTLRQVSFGLLDMAYYSADPAEVGSLFAFEKNAMKATELLPSVEGIMMSTSFSHIF
QGGYAAGYYSYKWAEVLDADAFELFLENGIFDPVTATSFKDNVLSAGGRVHPSVLYERFR
GRAPKPDALLKRAGLL