Protein Info for Echvi_2524 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: CRISPR-associated endoribonuclease Cas6

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 TIGR01877: CRISPR-associated endoribonuclease Cas6" amino acids 43 to 247 (205 residues), 66.4 bits, see alignment E=2.5e-22 PF01881: Cas_Cas6_C" amino acids 111 to 249 (139 residues), 72.4 bits, see alignment E=3.1e-24

Best Hits

Predicted SEED Role

"FIG00573375: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G1P0 at UniProt or InterPro

Protein Sequence (288 amino acids)

>Echvi_2524 CRISPR-associated endoribonuclease Cas6 (Echinicola vietnamensis KMM 6221, DSM 17526)
MRIRLIFSLKNKGAYLPFHHQYILAQFLKGLIVKGGREEFFNYNYFNFSGLKGQTKVSRS
GLHYYSSLVTLVLSSPNEDFLDYLLEQVFKTPKIELGNLIISPEYTEKESEPELEASNKF
VCISPLVLLTPTFDDDSGKRFINPDTDEFSDLLYESTLTRMERSGWYSQEQMESFYKFQV
VPDMNYVNKLKEQQKKFARIYSVYDMDVKYEVRGYTLPFTLYAAHEVQDFVFKCGLGAFT
HKGFGMLDLANNSPSQRTEPYKFKREGFVPYKSRQQQQDQPNKEEDEQ