Protein Info for Echvi_2487 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Fatty acid desaturase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00508, linoleoyl-CoA desaturase [EC: 1.14.19.3] (inferred from 59% identity to phe:Phep_0579)Predicted SEED Role
"Linoleoyl-CoA desaturase (EC 1.14.19.3)" (EC 1.14.19.3)
MetaCyc Pathways
- γ-linolenate biosynthesis II (animals) (2/2 steps found)
- arachidonate biosynthesis III (6-desaturase, mammals) (2/7 steps found)
- icosapentaenoate biosynthesis II (6-desaturase, mammals) (2/7 steps found)
- (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase) (3/13 steps found)
- docosahexaenoate biosynthesis III (6-desaturase, mammals) (3/14 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.14.19.3
Use Curated BLAST to search for 1.14.19.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0FXU5 at UniProt or InterPro
Protein Sequence (358 amino acids)
>Echvi_2487 Fatty acid desaturase (Echinicola vietnamensis KMM 6221, DSM 17526) MYPSLKFVDTENSRFFSTLKGRIDDYFHTNQLSKKANTAMVAKTVVYLIAFIGLYGLIIL EVFSPLITLSLAMLLGVTMACIGFNICHDALHGAYSTNSKVNKSLGFLFNIIGASEYVWR ITHNKIHHTYTNIIGHDGDLEVAPGLIRLSDKDKKKSVHRFQHVYAFLLYSLTSLSWFFR KDYLKFFQKNIGAHTNKHPKREYFNLFAYKAMYYTLFIIIPLGVMDIAWWQFLIGYLLMN FVEGLVLGLVFQLAHLVEETDMPSPKINEPIEAAWAVHQMRTTANFAVDSKTATFLCGGL NFQVEHHLFPNICHIHYPAISKILRKTAAEFNIPYINNGPFLTALGSHYRFLRKHGRN