Protein Info for Echvi_2406 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 74 to 91 (18 residues), see Phobius details amino acids 103 to 126 (24 residues), see Phobius details amino acids 133 to 153 (21 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 215 to 234 (20 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 300 to 319 (20 residues), see Phobius details amino acids 325 to 345 (21 residues), see Phobius details PF00953: Glycos_transf_4" amino acids 77 to 229 (153 residues), 138.1 bits, see alignment E=1.4e-44

Best Hits

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FXM3 at UniProt or InterPro

Protein Sequence (377 amino acids)

>Echvi_2406 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase (Echinicola vietnamensis KMM 6221, DSM 17526)
MYMFQLSTIPIAFFIGLLIIPVIIKVIKRTNILDVPGGRKIHKEAIPSMGGIGIVIAMLM
SLVITMDWQQWSDVRFLMMGFGVMFLVGLRDDLVELTAMQKLLGQLLAIGLVVVLGDIRV
SGFYGFLGIEELPVWVSYALTIFVIIGLTNAFNLVDGLDGLAGTLSLISFLFLGGWFLAA
GFLTYGMIALACSGGVLAFMVYNWHPAKIFMGDTGSLTLGFILAVLSVFFVEANGQILSP
AHFMRFEAPITAGLALVLVSCFDTLRVMVKRVRRGRPPMAADKSHVHHFLLRSGLRHDQV
ALVLGGIKLLFLCMVVSMADFSDNVLLPMVLGTVVVLCMTLDAVTLRKVKRIARQSPGVL
ATASEQEKRRELKEEPV