Protein Info for Echvi_2399 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: membrane protein insertase, YidC/Oxa1 family, N-terminal domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 360 to 381 (22 residues), see Phobius details amino acids 423 to 447 (25 residues), see Phobius details amino acids 477 to 498 (22 residues), see Phobius details amino acids 517 to 540 (24 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 3 to 352 (350 residues), 128.2 bits, see alignment E=5.7e-41 PF14849: YidC_periplas" amino acids 84 to 346 (263 residues), 98 bits, see alignment E=9.8e-32 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 360 to 554 (195 residues), 186.7 bits, see alignment E=4.7e-59 PF02096: 60KD_IMP" amino acids 361 to 554 (194 residues), 174 bits, see alignment E=2.5e-55

Best Hits

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 45% identity to dfe:Dfer_1150)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZC5 at UniProt or InterPro

Protein Sequence (598 amino acids)

>Echvi_2399 membrane protein insertase, YidC/Oxa1 family, N-terminal domain (Echinicola vietnamensis KMM 6221, DSM 17526)
MDRNQATGLILFAAVLLIYSFFFSSPEPVTDEQSTTSTEVQDDSASKQTAEPSTPALPDS
VKNLQNQQQFGEFSSLVEGKEESVVLENELVKITFSSKGGEIKSVELKNYKTWAKQPLIL
MDEQSASIDYQIQTNKGPMSLNQFYFVGEKSTVTVDETPAQQLTFKATTASGSITRTYTL
PDGKYVVDQQIKTNGLSSLSDQHINVLWEDRLKKQEADISESRRKTYVNFYTTEGDYDYL
SASSDEDAERPSEPIKWVAFKQRFFTAGIIAPDQFTEVSLEQTVPTDTMSVKNMTASLSL
PLENGQASNSYYFGPNNYKILKKVTPDFEKNVDMGYFFVSWVNKYIIVNLFHYLEKIISN
YGVIIILIVFIIKLFLFPLTYKSYIGMAKMRVIKPEIDELKEKYPDDPTKQQQEQMKLFS
QLGVSPISGCLPMILQMPFLFAMFFFFPNSIELRQESFLWAHDLSTYDSIINLPFTIPFY
GSHVSLFTLLMTVSQIVYTRFNNQLTAAQGPMKNLGYIMPVTFMFVLNSYPAALSFYYFV
SNMVTFGQQAIIKRFVDDDKIREKIEKNKKKNANKKKSKFQQRLEDAMKAAEANKKKK