Protein Info for Echvi_2347 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Fructose-2,6-bisphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 PF00300: His_Phos_1" amino acids 6 to 198 (193 residues), 156.7 bits, see alignment E=3e-50

Best Hits

KEGG orthology group: K01834, phosphoglycerate mutase [EC: 5.4.2.1] (inferred from 49% identity to mtt:Ftrac_1127)

Predicted SEED Role

"Hypothetical, related to broad specificity phosphatases COG0406" in subsystem Experimental tye

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.4.2.1

Use Curated BLAST to search for 5.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0G188 at UniProt or InterPro

Protein Sequence (210 amino acids)

>Echvi_2347 Fructose-2,6-bisphosphatase (Echinicola vietnamensis KMM 6221, DSM 17526)
MSTKKIYLVRHGQTDYNLKGVVQGSGIDAPINETGKKQAAAFYEAHKHIKFDRIYYTGLQ
RTRQSIERFLDNGTPYEALPDLNEISWGKYEGVPMSKDEHSYYQGMLEKWADGELDFSIE
GGESPNMVYARLKRGLDHILAQDGETILICMHGRAMRVMLSLMLKYDLRFMDIFEHHNLG
YYELTVKENGEFLLDRYNNVQHLKVKGLIG