Protein Info for Echvi_2265 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ATPase, YjeE family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 140 PF02367: TsaE" amino acids 12 to 129 (118 residues), 117.5 bits, see alignment E=1.9e-38 TIGR00150: tRNA threonylcarbamoyl adenosine modification protein YjeE" amino acids 14 to 133 (120 residues), 94.9 bits, see alignment E=1.9e-31

Best Hits

KEGG orthology group: K06925, UPF0079 ATP-binding protein (inferred from 53% identity to phe:Phep_4283)

Predicted SEED Role

"TsaE protein, required for threonylcarbamoyladenosine t(6)A37 formation in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZS9 at UniProt or InterPro

Protein Sequence (140 amino acids)

>Echvi_2265 ATPase, YjeE family (Echinicola vietnamensis KMM 6221, DSM 17526)
MKTIKCGTIATLPEVAKEIISYCRDLPVWVFQGEMGAGKTTLIKAVAKEFGVGDVVSSPS
FSIVNEYLNDQGETFYHFDFYRIKEQDEALEIGVDEYIYSGSYCWLEWAENIQDYLPEEF
YLIRIAVDDIGGREMSIKKF