Protein Info for Echvi_2026 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: N-acetylmuramic acid 6-phosphate etherase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 transmembrane" amino acids 203 to 219 (17 residues), see Phobius details TIGR00274: N-acetylmuramic acid 6-phosphate etherase" amino acids 8 to 268 (261 residues), 322.4 bits, see alignment E=1.1e-100 PF01380: SIS" amino acids 126 to 208 (83 residues), 29.1 bits, see alignment E=3.9e-11

Best Hits

Swiss-Prot: 63% identical to MURQ_BACTN: N-acetylmuramic acid 6-phosphate etherase (murQ) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K07106, N-acetylmuramic acid 6-phosphate etherase [EC: 4.2.-.-] (inferred from 63% identity to bth:BT_0133)

MetaCyc: 51% identical to N-acetylmuramic acid 6-phosphate etherase (Escherichia coli K-12 substr. MG1655)
RXN0-4641 [EC: 4.2.1.126]

Predicted SEED Role

"N-acetylmuramic acid 6-phosphate etherase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.-.-, 4.2.1.126

Use Curated BLAST to search for 4.2.-.- or 4.2.1.126

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWJ1 at UniProt or InterPro

Protein Sequence (274 amino acids)

>Echvi_2026 N-acetylmuramic acid 6-phosphate etherase (Echinicola vietnamensis KMM 6221, DSM 17526)
MSAQNALTTETSSLYEDLDKMNAQELLTSINQEDQKVAVAVQAAIPQIEKLITAAAEKMV
KGGRLFYIGAGTSGRLGILDASEIPPTYGASPELVCGLIAGGDSAIRHAVEGAEDDLDQA
WVDLKAQHITENDILIGIAASGRTPYVRGGLQTAKAHGVMTGSIACNANAQISGDADFPI
EVEVGPEFVTGSTRMKAGTAQKLVLNMISTSLMIMLGKVKGNKMVNMQLSNQKLVKRGTR
MILEEIPELDEGTALKLLTAHGSVKKAIDAYQNN