Protein Info for Echvi_1898 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 transmembrane" amino acids 23 to 44 (22 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details PF13675: PilJ" amino acids 49 to 136 (88 residues), 32.6 bits, see alignment E=1.5e-11 PF07730: HisKA_3" amino acids 410 to 474 (65 residues), 48.6 bits, see alignment E=1.9e-16 PF02518: HATPase_c" amino acids 515 to 610 (96 residues), 56.4 bits, see alignment E=7.5e-19

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYN6 at UniProt or InterPro

Protein Sequence (611 amino acids)

>Echvi_1898 Signal transduction histidine kinase (Echinicola vietnamensis KMM 6221, DSM 17526)
MLSNIGSMKNPHLSERPKFEKLVRYYLIALCAIATSIILSQILVQKFINEQKNDSRVVNL
SGRQRMLSQQISKYVLLLGDSLNRPKRSEYLSGLKSSLTEWKKVHIGLQFGDATLDIKGH
NSKTIRDLFGDIENDHAIMVSSAQQIIDKLEQDLSLPTDSLSHDINTLINHEQAFLNGMD
RIVFQYDDEAKDKVTNLQSIEIFLLILSLGVISFEIFFIFIPSAKTIRKTFKKLLVSEQK
AHKMTLEISSLYSSLEQAYQDLLEVDVAVDDYTVFAKSRPTGDFYYFSDKFSSIMEFDQA
PKNIFGWLQKQGYDSRYLDNIRKMTLSGRTWSGDIKVVNDMGDFVWIKINIIPTMGDDGE
VETLMVVATDETEKKEAEAISQEINKERIEKKVKEQQFRSALILEGQEEERKRISRDMHD
GIGQLLSAMKFNLEGIHSVKSDYEREKLKTSKDLLKNVIKEVRRISFNLTPSALSDYGIV
PVLNKFCREITKLSDLQVTFENQTGFLNRLEGKVENNLYRICQEAVNNAIKYAQASEVKI
VLSHNSQFLNVDIQDDGKGFDVNKLEEKGHLSASGHGLFNIRERANFINGQCTINSQIGK
GTTISINVPLD