Protein Info for Echvi_1805 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: DNA segregation ATPase FtsK/SpoIIIE and related proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 825 transmembrane" amino acids 37 to 60 (24 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details PF13491: FtsK_4TM" amino acids 40 to 205 (166 residues), 40.6 bits, see alignment E=4.4e-14 PF17854: FtsK_alpha" amino acids 339 to 438 (100 residues), 110.2 bits, see alignment E=1e-35 PF01580: FtsK_SpoIIIE" amino acids 449 to 650 (202 residues), 186.3 bits, see alignment E=1.1e-58 PF09397: FtsK_gamma" amino acids 752 to 812 (61 residues), 94.2 bits, see alignment 6.4e-31

Best Hits

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FW10 at UniProt or InterPro

Protein Sequence (825 amino acids)

>Echvi_1805 DNA segregation ATPase FtsK/SpoIIIE and related proteins (Echinicola vietnamensis KMM 6221, DSM 17526)
MASNTYKSNTFRKKEKAKKKKSSFNFSLGALKDKKIGLSFGILFMMIGLFLFFAFLGYLF
TGPADQSVVSGGNAEVTLRQNAAEARNWLGYAGAYVSHWLIFRWFGLAAFLLPPFLFLLG
FKWAFKKSLVPMTQYSAFALFFVFWLGLLLGYVVHILKGFSYLQFLSGGFGYEMAVLADE
FLGWGTFILIFGSLLIFVVFFFNITHIDWLQHDLKSDDPYIAPKPAAPVSRESNISEPSQ
EDEMEEDEEEVMMSDQEEEDEQSWTIKSAQPEKKKTPVSEPAFNIDDLETADDVQEKEKP
ADEKKFTVETTAHEEKKVSEVENLDPYDPTLDLPSYQYPSIDLLNEYDQQKVTVTRQELE
ENKNKIVETLVNFKIGIQEIKATIGPTVTLYEIVPDPGVKISKIKNLEDDIALSLAALGI
RIIAPIPGKGTIGIEVPNKNRELVAAGSVLGTEKFMKSDKDLPVALGKTISNEVFVFDLA
KMPHLLMAGATGQGKSVGLNVILASLVYKKHPSQLKFVLVDPKKVELTLFNKIERHFLAK
LPNAEDAIITDTKKVIYTLNSLCIEMDNRYDLLKDAGCRNLKEYNSKFVARKLNPEKGHK
FMPYIVLVIDELADLMMTAGKEIEGPIARLAQLARAIGIHLVVATQRPSVNVITGIIKAN
FPARLSFRVTSKVDSRTILDAGGAEQLIGMGDMLLSQGSDVIRLQCAFLDTPEVERVCEW
IGEQRGYSDAYLLPEFEGEDGDSSVGEVDLADRDPLFEDAARLIVMHQQGSTSLIQRKLK
LGYNRAGRIIDQLEAAGVVGAFEGSKAREVLIQDEVSLEQLLSSL