Protein Info for Echvi_1771 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Glycerol-3-phosphate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 473 to 494 (22 residues), see Phobius details PF01266: DAO" amino acids 17 to 373 (357 residues), 196.4 bits, see alignment E=2.1e-61 PF00890: FAD_binding_2" amino acids 17 to 57 (41 residues), 22.2 bits, see alignment 1.5e-08 PF16901: DAO_C" amino acids 417 to 500 (84 residues), 79.2 bits, see alignment E=5.1e-26

Best Hits

KEGG orthology group: K00111, glycerol-3-phosphate dehydrogenase [EC: 1.1.5.3] (inferred from 54% identity to psn:Pedsa_2891)

Predicted SEED Role

"Glycerol-3-phosphate dehydrogenase (EC 1.1.5.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization or Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Respiratory dehydrogenases 1 (EC 1.1.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FZ81 at UniProt or InterPro

Protein Sequence (521 amino acids)

>Echvi_1771 Glycerol-3-phosphate dehydrogenase (Echinicola vietnamensis KMM 6221, DSM 17526)
MNRAHNLRPLAKNQLWDIVIIGGGASGLGVALDALSRGLSVALFERADFAKGTSSRSTKL
VHGGVRYLAQGDILLVWEALRERGRILKNAPHLAHAQPFIIPIYSHATKYYYTVGLKFYD
WMSGWLSLGDSSFISKKETIKRLPEIKTEGLLGGVVYHDGAFDDARLAIAVAQTCDDMGG
CILNYMKVTSLTKDGAGIITGVKVRDAIHKKSYDVKAKMVVNATGVFADKILQMDQKGAP
RMIQPSQGVHLVLPQHFLGGQDALMIPKTSDGRVLFAVPWQGKLVVGTTDTIRAKTKMEP
EALSREINFILANAGQYLSKKPTRKDVLTVYAGLRPLAAPKGESVKTKEISRNHKVIISD
SGLTTLTGGKWTTFRKMGEDTVDHFPRVTGEEIKESHSWEIKLHGHGDPTLDDKHWKIYG
TDAVKILQLIKENPPYAKLLHPQYPYVAGEVIWAIREEMAMHIEDFLARRIRILLLDAAA
AIAMAPLVASLMAAELKKDKNWIDNEVSAFTKIAEKYLIKP