Protein Info for Echvi_1576 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Predicted dehydrogenases and related proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF01408: GFO_IDH_MocA" amino acids 44 to 167 (124 residues), 69.6 bits, see alignment E=4e-23 PF02894: GFO_IDH_MocA_C" amino acids 180 to 440 (261 residues), 80.3 bits, see alignment E=1.9e-26

Best Hits

KEGG orthology group: None (inferred from 57% identity to avi:Avi_5579)

Predicted SEED Role

"Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18)" in subsystem Inositol catabolism (EC 1.1.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.18

Use Curated BLAST to search for 1.1.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYK2 at UniProt or InterPro

Protein Sequence (457 amino acids)

>Echvi_1576 Predicted dehydrogenases and related proteins (Echinicola vietnamensis KMM 6221, DSM 17526)
MSDQTTNLHRRRFLSKTGALAAGSFFIHPIAKALNLRENPAQKLRVALVGTGIRGTSMFG
RSIVEDYPNEVEFVGLSDINEGRLAYGKTYIGVDCPTFVDFDEMMATVKPDVLIVTTMDS
THDQFIIKGLEAGANVITEKPMTTDEVKCQNILDAERRTGKQVIVTFNYRYSPHRQKIYE
LLHGGEIGEVTSVDFHWYLDTDHGTSYFRRWHGYREKGGTLLVHKATHHFDLLNWWLDSD
PAEVFAFGKLEFYGKNGPYRSTNCRPCPHKDDCDFYWDITKSKRLMDLYVANEEYDGYLR
DGCVYREDIDIYDKMAVQIRYMNDVQVSYSLTTYSPYEGYRIAFNGTKGRLEAWIKESQP
WEEKPADELRLTKNFGDTEIITIPHTGGGHGGGDVRLKDKLFKDPNMADPYRQSAGTRDG
AMSILIGIAARKSIETNKPVYISDLVDIKLQAKRPKG