Protein Info for Echvi_1560 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1089 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07676: PD40" amino acids 58 to 92 (35 residues), 21.6 bits, see alignment (E = 4.2e-08) amino acids 342 to 373 (32 residues), 25.8 bits, see alignment (E = 2e-09) amino acids 442 to 457 (16 residues), 12.4 bits, see alignment (E = 3.2e-05) PF14684: Tricorn_C1" amino acids 694 to 760 (67 residues), 94.8 bits, see alignment 6.7e-31 PF14685: Tricorn_PDZ" amino acids 774 to 863 (90 residues), 78 bits, see alignment E=1.1e-25 PF03572: Peptidase_S41" amino acids 892 to 1047 (156 residues), 75.8 bits, see alignment E=7.5e-25

Best Hits

KEGG orthology group: K08676, tricorn protease [EC: 3.4.21.-] (inferred from 53% identity to lby:Lbys_1398)

Predicted SEED Role

"tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins" in subsystem Ton and Tol transport systems

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FYV4 at UniProt or InterPro

Protein Sequence (1089 amino acids)

>Echvi_1560 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system (Echinicola vietnamensis KMM 6221, DSM 17526)
MFKKLSKLLGAALLVPFVSWAQLDAKIAQYPDVSDTHITFSYGGDIWIVPKTGGLANRLT
TSKGTESFPKFSPDGSKVAFSGVYNGNSDVYVMPFQGGMPQRLTYHGMSDRMVDWYGDGN
HILFASSRESEKQRYNQFYKVSVDGGLPEKLPVPYGEFGMISPDGNKIAYTPKSRAFRTW
KRYKGGMATDIFTFDLASNASENISNSIYNDEFPMWTADKIYFLSDRGAHQRNNIYSYDL
ATKEIAQITDFSAYDVLFPSIGKDEIVFTAGGEIYLLDLSSGEFEAVSIQVSSDVTALMP
RKENVKRYIQNVWPSYDGNRAVFEARGELFSVPAKDGPVINLTQSSGVAERYPAWSPDGR
YVAYWSDRTGEYELTIKDLKNGGAEKTLSAYGAGYRYQLYWSPDSKKVAFVDKAMDIYVY
DKEKDKTTHVDKQKSLFQYGLDNFSVSWSPDSRYLAFEKNLTNQHNAIAVFDIEEEALHQ
ITSGFYSDNNPVFGPEGKYLYCLTNRDFDPVYSDFEGTWVYANATQLAAIPLLKETASPL
APKNDSTSVKEEEQSAKEEDKSKKSKKDKSDDADTEEDSDKVKIDWDGLERRMVVLPPSA
GNYSSLGAVKGKVLYLKHPTNGSDSHQSELAYYDVEARESKTIMGNVSGYRLTANGEKAL
VVSQGSFGIIGIGEGKKLEDKMPTDKIEMILEPKAEWRQIFNDAWRLERDFFYDPNMHGV
DWEAMRDHYGKLIDHAITREDVNYIIGELIGEISASHTYRGGGDTESTSSKSIGYLGIDW
GEKDDAYFVKEIIRGAPWDSEARSPLDEAGVDISEGDFILAVNGVPIDMEKDPWAAFEDL
AGETVELTVNDQASLDGSKKVMVKTLGTETRLRNLAWIEENRKRVEEATDGKIGYIYVPS
TGYDGQQELARMFYAQFDKEGLIIDERFNNGGQIPDRFVELLNRKPLAFWAVRDGETWQW
PQVANFGPKVMLINGWSGSGGDAFPDYFRKAGLGPLIGTRTWGGLIGISGAPSLIDGGSV
TVPTFRMFDPSGEWFKEGHGVDPDIEVAEDPTALANGTDPQLEKAIEETLRLLKQQPSVQ
PKVPAYEVK