Protein Info for Echvi_1486 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: CotH protein.

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1147 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF00932: LTD" amino acids 32 to 142 (111 residues), 70.4 bits, see alignment E=4.2e-23 PF13290: CHB_HEX_C_1" amino acids 191 to 224 (34 residues), 22.6 bits, see alignment (E = 2.1e-08) PF13287: Fn3_assoc" amino acids 201 to 319 (119 residues), 25.4 bits, see alignment E=3.2e-09 PF08757: CotH" amino acids 405 to 739 (335 residues), 130.9 bits, see alignment E=2e-41 PF18962: Por_Secre_tail" amino acids 1072 to 1145 (74 residues), 45 bits, see alignment 2.8e-15 TIGR04183: Por secretion system C-terminal sorting domain" amino acids 1072 to 1146 (75 residues), 38.2 bits, see alignment 5.6e-14

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWR8 at UniProt or InterPro

Protein Sequence (1147 amino acids)

>Echvi_1486 CotH protein. (Echinicola vietnamensis KMM 6221, DSM 17526)
MENIYEPLLFTKMHKFLFFCTLLFFINFGVKSQQITINEVMSSNDGSFYDDDNDDEDWIE
LYNYGESAINLGGFSLTDDKDETDKWEFPDFTLQPGAYLLIWASGKNKKDSMSPLHTNFS
ISADGEALYLFTPDNEEISKIDVPPVPTNYSYGRFPNGTGDWYFYNSPSPKKSNGENGQS
NLLSPPTFSTPPGWYSQPTTIELTSSVPEAMILYTLDGSIPDINNLDGEGIPFLINYFHF
GEWNESKNISRRNTTYVYTTPLQLSDKTSKDNDLSDIITTYRTDFGHGWKRPQENVFKGQ
VIRTATYKDGNISPVNTGSFLFHPDKNNRYELPIISLVSSQENLFGHEEGIYVQGKEYFD
AGGTEHSYVSVANYYHRGKDWEKQVHLEFFLKNGKLDFSQNLGTRIHGGGSRSKPMKSLR
LYGRNEYDSDNEMAYTFLPEASDAFGNTMESYKHLLLRAGGDYMDIYTDAVSQKIMSPAK
VDLQDSRPSILLLNGEFWGIINLRERLNDHHISRKYHVKDDNLIILNAPWGNGSESQVET
GEPSDISYYRNLYQFAIDKDLSQETNYSYIEEHLDVLSYVDYNIMFIYMNNTDWDGEKHF
RYWRTKETSSKPYEDGKWRLMIWDFDASARYQAPASYDFLDNFIHPEGGGEFRPTGDPEK
TALLRSLLTNASFRNLFINRFADHINTTFHPDRTARIIQERYQELQPHLEEHFKRWNHHG
TNEDRKNELITYFKERPNYQRKHIEDHFNIEEDLKLTLDVSNPNHGFIKCNTIDIKPSTP
GIPDQSYPWNGTYFKNIPVTLEAKPMEGFEFHHWAVGEERYNDPTITLSLEENTKALAVF
TPTEEQSQRLIHFWHFDKDNVENDVALTQIEASYSLTGSNAVLHFQPVIPYYPPPSGTAG
IMDRVNDPTPINYREKGNRGKPYLSNQMRGIRTRNPLVMSGKEAFLVFEIPTNNFKDIIL
SMAISRTGSGPEKALIEYTMDGEEWISDQLETKEILLEEDFKLVSMDFTSILGANNNKDF
KVRLKFSGPTVFGDAGNARFNNVSVDGYLIEDVITDLPSNPEETPGNYLEKIYPNPTNDK
LNLKFKGDSHSNIRYMEIINSNGNIINKIDNIPSNQITISTSAFPTGLYTLKIVTNQKIE
ISKFIKL