Protein Info for Echvi_1431 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Superoxide dismutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00081: Sod_Fe_N
  • amino acids 60 to 139 (80 residues), 73.9 bits, E=1.2e-24
• PF02777: Sod_Fe_C
  • amino acids 146 to 251 (106 residues), 140.9 bits, E=1.3e-45

Best Hits

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 52% identity to hne:HNE_1624)

Predicted SEED Role

"Manganese superoxide dismutase (EC 1.15.1.1)" in subsystem Nitric oxide synthase or Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• superoxide radicals degradation (2/2 steps found)
• ethene biosynthesis III (microbes) (5/7 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Sequence Analysis Tools

See L0FWL3 at UniProt or InterPro

Protein Sequence (256 amino acids)

>Echvi_1431 Superoxide dismutase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKSSFNPSRRTFITQSTKATLAVGIGSSALGSAFLTACGASKEEEEKAVQLSTGFSQAG
LTYDYGALEPNIDATTMEIHYTKHAAGYARKLKAACEEEGVDMSKPLEEVLMNVSNYSTA
MRNNGGGHYNHELFWSIMSPEGGGKPEGELASAIDKAFGSFDAFVEKFEGEAKGRFGSGW
AWLVLDANKKLKVGSTPNQDNPLMDVSDLQGIPLMGIDVWEHAYYLHYQNERGKYVSNWW
NVVNWAAVQERYVAIV