Protein Info for Echvi_1163 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Endoglucanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF19190: BACON_2
  • amino acids 33 to 114 (82 residues), 46.2 bits, E=5.3e-16
• PF13004: BACON
  • amino acids 57 to 114 (58 residues), 42.1 bits, 1.1e-14
• PF00150: Cellulase
  • amino acids 153 to 445 (293 residues), 183.6 bits, E=8.5e-58

Predicted SEED Role

"Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Xylose utilization (EC 3.2.1.8)

MetaCyc Pathways

• (1,4)-β-D-xylan degradation (2/2 steps found)
• cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.8

Use Curated BLAST to search for 3.2.1.8

Sequence Analysis Tools

See L0FU56 at UniProt or InterPro

Protein Sequence (475 amino acids)

>Echvi_1163 Endoglucanase (Echinicola vietnamensis KMM 6221, DSM 17526)
MHQNNRVVSLIFLFLLLGMEWACKSSEEEPSKLDVSSTRIELEADGESKEVSISSNTAWS
AHASANWINMTPSSGTGSQTVSIAALANTTPDSREAVVQIVAGSLQREIQVSQAAGKSHP
SYYIPADQTEMREISSLELAPELGIGWNLGNSLEAIGGETAWGNPAVTKELIDAVKAAGF
SAVRIPVAWSKFTDESSFTIDPAWAERVEEVVNYVLDNDLYAIINIHWDGGWMQPTYVAE
DAVNARLEAMWVQIALHFRDYDDHLLFAGTNEVMVDGDYGQPTPEYRTVQNGYNQTFVNA
VRGTGGRNAYRHLVVQSFNTNIDHAVDFMEMPVDEVKDRLMAEVHYYDPYEFALDADSPV
SEWGANADNPSKTAGWGGEAYATGQFKKMKSHFVDKGIPVIVGEYGAISKTNLEDHAVYR
AYYLEWITQAMLDQSLVPFYWDNGHTGNHGFGLFDRNNGEQVYPDLIDKITPSIN