Protein Info for Echvi_1160 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Alpha-L-fucosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF01120: Alpha_L_fucos" amino acids 65 to 342 (278 residues), 124.3 bits, see alignment E=1.7e-39 PF00754: F5_F8_type_C" amino acids 360 to 465 (106 residues), 48.8 bits, see alignment E=1.6e-16 amino acids 571 to 674 (104 residues), 52.9 bits, see alignment E=8.4e-18 PF13290: CHB_HEX_C_1" amino acids 495 to 550 (56 residues), 58 bits, see alignment 1.5e-19 PF13287: Fn3_assoc" amino acids 496 to 550 (55 residues), 53 bits, see alignment 6.2e-18

Best Hits

Predicted SEED Role

"Alpha-L-fucosidase (EC 3.2.1.51)" in subsystem L-fucose utilization or L-fucose utilization temp (EC 3.2.1.51)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.51

Use Curated BLAST to search for 3.2.1.51

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FXE6 at UniProt or InterPro

Protein Sequence (684 amino acids)

>Echvi_1160 Alpha-L-fucosidase (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKYLALLLVAFSCQQKEVAPPDPVAPVPSERQLAWQELEFYAFIHFNMNTFSNMEWGMG
DEDPDTFNPTALDCRQWAKVAKDAGMKGIIITAKHHDGFCLWPTETTAHSVKNSSWKDGK
GDVIKELAEACREYGLKFGVYLSPWDRNSPHYGTPAYIDIFRAQLKELLTNYGDVFEVWF
DGANGGTGYYGGANEERRVDKKNYYDWENTYKIIRELQPEAVIFSDAGPDLRWVGNEEGH
AYKTTWSNLMRDEVYGGMPNYSADYSAGQENGTHWVPAEVDVSIRPGWYYHPYEDHKVKS
LPKLLDIYYESLGRNGSLLLNFPVDRRGLIHEKDAEQVQKLADKVKEDFAHNLAVEKGEI
AASETRGAGFEAQLAVDEDASTYWATSDGKVSGSLTVTFDEPTTFNRFLAQEYIALGQRV
KAFTVEVQTDRGWEEIANETTIGYRRILRFPEVTATALRFTVTDAKACPTISELGIYLAP
KVILAPEISRSVEGMVSLDAADEGLEIYYTTDGSNPTKDSKAYAEPFEVKSPMTVQAIVM
DPSTGKISEVGRVDFDLAKEGWKVINGADKSGQAIDEDIRTNYISENDAVVIDLGATVDL
KGFTYMPMQNRYMSGVIQDYAFAVSSNGTNWKTVSKGEFGNIAASPIEQKITFDPEKARY
IRLTATKTLDGNKASFAEIGVITK