Protein Info for Echvi_1138 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: excinuclease ABC, A subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 946 TIGR00630: excinuclease ABC subunit A" amino acids 12 to 925 (914 residues), 1354.9 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 138 to 243 (106 residues), 115.1 bits, see alignment E=4.4e-37 PF17755: UvrA_DNA-bind" amino acids 297 to 399 (103 residues), 70.5 bits, see alignment E=4.2e-23

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 66% identity to aas:Aasi_0942)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FU28 at UniProt or InterPro

Protein Sequence (946 amino acids)

>Echvi_1138 excinuclease ABC, A subunit (Echinicola vietnamensis KMM 6221, DSM 17526)
MSKTVAAVEETIEIYGAREHNLKNLDLSIPRNKLVVITGLSGSGKSSLAFDTIYAEGQRR
YMESFSAYARSFLGGMERPDVDKINGLSPVISIEQKTTSKNPRSTVGTVTEIYDFMRLLY
ARSGEAYSYLSGKKMIRQTEDQIIDQLLEHFAGKKLYILAPVVKGRKGHYRELFEQIRKM
GFSKVRVDGVVMEMVPKMQVDRYKIHDIEIVVDRIIAEEDDRYRITQSLKTALQHGKGII
MLRDEEGNVHHFSKYLMDPTTGLSYDEPAPNTFSFNSPYGACPTCNGIGVIEEITKENII
PDPNLSISRGGIVPIGEYRDIWIFKKIEAILKRHKASLSTPIKDLKEEVLDVLLYGDKTA
VEVDSVKYPGTKWSTTFEGIVNFLQKQQEGGSEKIQKWVSDFTTTRECPDCEGYRLKKEA
LHFLIAGKHIGELAMMDIRQLGNWFDQIDDKLTEKQKIIGEEVLKEIRKRIGFLLDIGLD
YLSLNRPLRTLSGGEAQRIRLATQIGTQLVGVLYILDEPSIGLHQRDNVKLIKALQDLRD
LGNSVLVVEHDKDMMLDADYVVDIGPGAGRHGGHIVAKGSPKEILQQNSLTAKYLNGKEE
IAIPQERRKGSGNFLTLLQASGHNLKNVDLELPLGSMICVTGVSGSGKSSLIHETLFPLL
NQHFYRSRKTPLPYGSIKGLEHLDKVIEVDQSPIGRTPRSNPATYTGVFTDIRALFTELP
EAKIRGYKPGRFSFNVKGGRCEDCEGAGMKLIEMDFLPDVHIPCETCKGKRYNRETLEVR
FKGKSISDVLDMTVEQAVEFFENQPKILRKIQTLNDVGLGYITLGQHATTLSGGEAQRVK
LATELSKKDTGKTFYILDEPTTGLHFKDIEHLLEVLNRLVEKGNTVLIIEHNLDVIKVAD
HIIDLGPEGGNKGGQILAQGTPEEVSKHPSSYTAKFLRMELSPSKA