Protein Info for Echvi_1089 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: PAS domain S-box

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 593 PF00989: PAS" amino acids 4 to 110 (107 residues), 41.7 bits, see alignment E=4.8e-14 amino acids 121 to 222 (102 residues), 51.3 bits, see alignment E=4.9e-17 amino acids 241 to 351 (111 residues), 51.6 bits, see alignment E=4e-17 TIGR00229: PAS domain S-box protein" amino acids 4 to 113 (110 residues), 27.9 bits, see alignment E=1.1e-10 amino acids 122 to 240 (119 residues), 91.9 bits, see alignment E=1.7e-30 amino acids 238 to 357 (120 residues), 73.3 bits, see alignment E=1e-24 PF08448: PAS_4" amino acids 6 to 112 (107 residues), 27.2 bits, see alignment E=1.8e-09 amino acids 125 to 235 (111 residues), 29.9 bits, see alignment E=2.6e-10 amino acids 245 to 356 (112 residues), 39.1 bits, see alignment E=3.5e-13 PF13426: PAS_9" amino acids 17 to 108 (92 residues), 23.3 bits, see alignment E=2.9e-08 amino acids 128 to 233 (106 residues), 49.2 bits, see alignment E=2.6e-16 amino acids 249 to 354 (106 residues), 62.1 bits, see alignment E=2.4e-20 PF13188: PAS_8" amino acids 239 to 304 (66 residues), 33.1 bits, see alignment E=1.7e-11 PF00512: HisKA" amino acids 376 to 441 (66 residues), 40.5 bits, see alignment E=1.1e-13 PF02518: HATPase_c" amino acids 484 to 592 (109 residues), 81.7 bits, see alignment E=2.4e-26

Best Hits

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-)" in subsystem Oxidative stress or Oxygen and light sensor PpaA-PpsR (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FXH4 at UniProt or InterPro

Protein Sequence (593 amino acids)

>Echvi_1089 PAS domain S-box (Echinicola vietnamensis KMM 6221, DSM 17526)
MDSQVFSNARDAILAFDLRGNVVYSNAASYKLFEYNRSSLLGMEYGALVHEAKMDFDQLR
EAILFNETLDPFKFNIVSKGDRKKLVSAQFSPVKDEDGKITGISVFFRKVNQSDKVASKA
QALVETAPDAMVIVNSEGQIVLINAQTENQFGYNKEELIGSELEILIPDKYISKHKQNRK
SYAKQPKPRSMGQGMELFGKRKDGSVFPVEISLSPLKTEDGLFVSAAIRNITDRKKAENK
FKGLLESAPDAIILADKDGNIQLANEQVVNIFGYSKSELIGNKIEMLVPMRYHHRHTNHR
DEFFHTAETRPMASGLELSGVRKSGEEFPVEISLSPLETEDGALAIAVIRDTSEKAAVKK
EMQDFNKKLQVKNKELEQFAYVASHDLQEPLQTVMSFTEFLSENYGEHFDETGKKSMQYI
MEATGRMRQLIKGLLDYSRIGRERKPVMVDCNSLISDIKVDLSSQIKATNASIHADNLPH
IKGNYTELRLLFQNLITNGIKFHQEGVPPKIQIGVTKKADHWLFCIKDNGIGIENKFKER
IFIIFQRLHTRNTYDGTGIGLAHCQKIVELHGGKIWVHSELGKGSSFLFTVPN