Protein Info for Echvi_0968 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: deoxyguanosinetriphosphate triphosphohydrolase, putative

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 TIGR01353: putative dGTPase" amino acids 26 to 439 (414 residues), 341.4 bits, see alignment E=5.2e-106 PF01966: HD" amino acids 63 to 133 (71 residues), 25.6 bits, see alignment E=1.3e-09 PF13286: HD_assoc" amino acids 337 to 438 (102 residues), 30.4 bits, see alignment E=4.7e-11

Best Hits

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 54% identity to mtt:Ftrac_2393)

Predicted SEED Role

"Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)" in subsystem Purine conversions (EC 3.1.5.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.5.1

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FTJ9 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Echvi_0968 deoxyguanosinetriphosphate triphosphohydrolase, putative (Echinicola vietnamensis KMM 6221, DSM 17526)
MKWEKLLSAGRADFKQRAHQSQEQYRSEFERDYDRIIFSAPFRNLQDKTQVFPLPEVDFV
HTRLTHSLEVSSVGRSLGKSAGEYLLKKYPALSERGIGSSDIGAIVAAAALTHDIGNPPF
GHAGEDAISDFFRFHPSGQRWKDHLREEEWMDMTHFEGNAQGFRMLLDKNNGLQVCYATL
AAFTKYPRPAWVKEADPGRRSQKKFGFFADQLGLFKQVADTLGIPPSGENTWHRHPLAFL
VEAADDICYSIIDLEDGCTLGLVQLAETIPLLAEIIGDKFQEDKLQSLKTSAQKLAILRA
MAISKLVEETVEAFRTHEEEMLAGTFDQALTECIPSAAALKKITKLSVAKIYRSQPVLEK
EAAGFQVLEGLLEVFSDALYNQYFDTERFSGKDKSILRLLPEVFKPDNELQMPYLLLRNL
VDFIAGMTDKYALSLYRKVKGIALPGT